Relaxin and its role in the development and treatment of fibrosis.
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Novel insights into the bovine polled phenotype and horn ontogenesis in BovidaeSerelaxin treatment promotes adaptive hypertrophy but does not prevent heart failure in experimental peripartum cardiomyopathy.Serelaxin: a novel therapy for acute heart failure with a range of hemodynamic and non-hemodynamic actionsRelaxin signals through a RXFP1-pERK-nNOS-NO-cGMP-dependent pathway to up-regulate matrix metalloproteinases: the additional involvement of iNOS.Cyclic nucleotide signalling in kidney fibrosis.Relaxin does not improve Angiotensin II-induced target-organ damage.International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.Relaxin regulates myofibroblast contractility and protects against lung fibrosisRelaxin inhibits cardiac fibrosis and endothelial-mesenchymal transition via the Notch pathway.The Anti-fibrotic Actions of Relaxin Are Mediated Through a NO-sGC-cGMP-Dependent Pathway in Renal Myofibroblasts In Vitro and Enhanced by the NO Donor, Diethylamine NONOate.Relaxin and atrial natriuretic peptide pathways participate in the anti-fibrotic effect of a melon concentrate in spontaneously hypertensive rats.Relaxin Receptor RXFP1 and RXFP2 Expression in Ligament, Tendon, and Shoulder Joint Capsule of Rats.Combining an epithelial repair factor and anti-fibrotic with a corticosteroid offers optimal treatment for allergic airways disease.Hanging in the balance: endogenous anti-inflammatory mechanisms in tissue repair and fibrosis.Host-directed therapeutics for tuberculosis: can we harness the host?Relaxin augments BMP-2-induced osteoblast differentiation and bone formation.Down-regulation of collagen synthesis and matrix metalloproteinase expression in myofibroblasts from Dupuytren nodule using adenovirus-mediated relaxin gene therapy.Relaxin is up-regulated in the rat ovary by orthodontic tooth movement.Relaxin-like peptides in male reproduction - a human perspective.Novel Anti-fibrotic Therapies.Expression of RXFP1 Is Decreased in Idiopathic Pulmonary Fibrosis. Implications for Relaxin-based Therapies.Relaxin signaling activates peroxisome proliferator-activated receptor gamma.Serelaxin increases the antifibrotic action of rosiglitazone in a model of hepatic fibrosisRelaxin decreases the severity of established hepatic fibrosis in miceCombination therapy with relaxin and methylprednisolone augments the effects of either treatment alone in inhibiting subepithelial fibrosis in an experimental model of allergic airways disease.Simultaneously Targeting Myofibroblast Contractility and Extracellular Matrix Cross-Linking as a Therapeutic Concept in Airway Fibrosis.Pathways to Precision Medicine in Idiopathic Pulmonary Fibrosis. Time to Relax?Intranasally administered serelaxin abrogates airway remodelling and attenuates airway hyperresponsiveness in allergic airways disease.The actions of relaxin on the human cardiovascular system.
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Relaxin and its role in the development and treatment of fibrosis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 22 April 2009
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Relaxin and its role in the development and treatment of fibrosis.
@en
Relaxin and its role in the development and treatment of fibrosis.
@nl
type
label
Relaxin and its role in the development and treatment of fibrosis.
@en
Relaxin and its role in the development and treatment of fibrosis.
@nl
prefLabel
Relaxin and its role in the development and treatment of fibrosis.
@en
Relaxin and its role in the development and treatment of fibrosis.
@nl
P2860
P1476
Relaxin and its role in the development and treatment of fibrosis.
@en
P2093
Robert G Bennett
P2860
P356
10.1016/J.TRSL.2009.03.007
P577
2009-04-22T00:00:00Z