Verteporfin, a suppressor of YAP-TEAD complex, presents promising antitumor properties on ovarian cancer
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Screening-based approaches to identify small molecules that inhibit protein-protein interactions.Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.Drug development against the hippo pathway in mesotheliomaVerteporfin inhibits growth of human glioma in vitro without light activationTargeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function.Combinatorial Microenvironments Impose a Continuum of Cellular Responses to a Single Pathway-Targeted Anti-cancer Compound.C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC.Clinical Implications of the Hippo-YAP Pathway in Multiple Cancer Contexts.Active epithelial Hippo signaling in idiopathic pulmonary fibrosis.Hippo-yap signaling in ocular development and disease.YAP/TAZ Activation as a Target for Treating Metastatic Cancer.Verteporfin inhibits YAP-induced bladder cancer cell growth and invasion via Hippo signaling pathway.Epithelioid Hemangioendothelioma as a Model of YAP/TAZ-Driven Cancer: Insights from a Rare Fusion SarcomaFolic Acid Has a Protective Effect on Retinal Vascular Endothelial Cells against High GlucoseVerteporfin selectively kills hypoxic glioma cells through iron-binding and increased production of reactive oxygen speciesRepurposing of Drugs Targeting YAP-TEAD Functions
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Verteporfin, a suppressor of YAP-TEAD complex, presents promising antitumor properties on ovarian cancer
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 August 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Verteporfin, a suppressor of Y ...... r properties on ovarian cancer
@en
Verteporfin, a suppressor of Y ...... properties on ovarian cancer.
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type
label
Verteporfin, a suppressor of Y ...... r properties on ovarian cancer
@en
Verteporfin, a suppressor of Y ...... properties on ovarian cancer.
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prefLabel
Verteporfin, a suppressor of Y ...... r properties on ovarian cancer
@en
Verteporfin, a suppressor of Y ...... properties on ovarian cancer.
@nl
P2093
P2860
P356
P1476
Verteporfin, a suppressor of Y ...... r properties on ovarian cancer
@en
P2093
P2860
P304
P356
10.2147/OTT.S109979
P407
P577
2016-08-29T00:00:00Z