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Acetylcorynoline impairs the maturation of mouse bone marrow-derived dendritic cells via suppression of IκB kinase and mitogen-activated protein kinase activitiesAutophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulationEvidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activityThe "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting gliaThe emerging role of Toll-like receptor 4 in myocardial inflammationMultiple roles of toll-like receptor 4 in colorectal cancerSubversion of host recognition and defense systems by Francisella sppEvidence that opioids may have toll-like receptor 4 and MD-2 effectsBasic principles and emerging concepts in the redox control of transcription factorsTLR4 activates the β-catenin pathway to cause intestinal neoplasiaRole for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/AktA novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein I antibodies.Long-term results of the phase II trial of the oral mTOR inhibitor everolimus (RAD001) in relapsed or refractory Waldenstrom Macroglobulinemia.Decreased TLR4 expression on monocytes may cause regulatory T cells abnormality in patients with primary immune thrombocytopenia.High-throughput screening for TLR3-IFN regulatory factor 3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors.Toll-like receptor signaling in cell proliferation and survivalToll-Interacting Protein in Resolving and Non-Resolving Inflammation.Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effectsToll-like receptor 4 plays a central role in cardiac dysfunction during trauma hemorrhage shockDominant role of the MyD88-dependent signaling pathway in mediating early endotoxin-induced murine ileusSignaling through FcRγ-associated receptors on dendritic cells drives IL-33-dependent TH2-type responses.The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cellsNetwork topologies and dynamics leading to endotoxin tolerance and priming in innate immune cells.PreImplantation factor promotes neuroprotection by targeting microRNA let-7Absence of Appl2 sensitizes endotoxin shock through activation of PI3K/Akt pathway.FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages.Lipoteichoic acid from Staphylococcus aureus induces lung endothelial cell barrier dysfunction: role of reactive oxygen and nitrogen speciesIntracellular trafficking of AIP56, an NF-κB-cleaving toxin from Photobacterium damselae subsp. piscicidaNon-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in miceInduction of PLSCR1 in a STING/IRF3-dependent manner upon vector transfection in ovarian epithelial cellsPharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammationResistin increases monolayer permeability of human coronary artery endothelial cells.Role of phosphoinositide 3-kinase-Akt signaling pathway in the age-related cytokine dysregulation in splenic macrophages stimulated via TLR-2 or TLR-4 receptorsIsotretinoin and FoxO1: A scientific hypothesis.The transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells.Therapeutic Developments Targeting Toll-like Receptor-4-Mediated NeuroinflammationEscherichia coli Maltose-Binding Protein Induces M1 Polarity of RAW264.7 Macrophage Cells via a TLR2- and TLR4-Dependent MannerTLR4-mediated AKT activation is MyD88/TRIF dependent and critical for induction of oxidative phosphorylation and mitochondrial transcription factor A in murine macrophages.Panax Notoginseng flower saponins (PNFS) inhibit LPS-stimulated NO overproduction and iNOS gene overexpression via the suppression of TLR4-mediated MAPK/NF-kappa B signaling pathways in RAW264.7 macrophagesAcetylbritannilactone Modulates MicroRNA-155-Mediated Inflammatory Response in Ischemic Cerebral Tissues.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
TLR4/MyD88/PI3K interactions regulate TLR4 signaling.
@en
TLR4/MyD88/PI3K interactions regulate TLR4 signaling.
@nl
type
label
TLR4/MyD88/PI3K interactions regulate TLR4 signaling.
@en
TLR4/MyD88/PI3K interactions regulate TLR4 signaling.
@nl
prefLabel
TLR4/MyD88/PI3K interactions regulate TLR4 signaling.
@en
TLR4/MyD88/PI3K interactions regulate TLR4 signaling.
@nl
P2093
P2860
P356
P1476
TLR4/MyD88/PI3K interactions regulate TLR4 signaling.
@en
P2093
Andrei E Medvedev
Darren J Perkins
Matthew J Fenton
Michelle H W Laird
Sang Hoon Rhee
Stefanie N Vogel
Wenji Piao
P2860
P304
P356
10.1189/JLB.1208763
P577
2009-03-16T00:00:00Z