Restoring the procofactor state of factor Va-like variants by complementation with B-domain peptides
about
Biology of tissue factor pathway inhibitor.Platelets contain tissue factor pathway inhibitor-2 derived from megakaryocytes and inhibits fibrinolysis.Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models.Novel insights into the regulation of coagulation by factor V isoforms, tissue factor pathway inhibitorα, and protein S.Pro- and anticoagulant properties of factor V in pathogenesis of thrombosis and bleeding disorders.Rethinking events in the haemostatic process: role of factor V and TFPI.Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation.The C-terminus of tissue factor pathway inhibitor-α inhibits factor V activation by protecting the Arg1545 cleavage site.
P2860
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P2860
Restoring the procofactor state of factor Va-like variants by complementation with B-domain peptides
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Restoring the procofactor stat ...... ntation with B-domain peptides
@en
Restoring the procofactor stat ...... tation with B-domain peptides.
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type
label
Restoring the procofactor stat ...... ntation with B-domain peptides
@en
Restoring the procofactor stat ...... tation with B-domain peptides.
@nl
prefLabel
Restoring the procofactor stat ...... ntation with B-domain peptides
@en
Restoring the procofactor stat ...... tation with B-domain peptides.
@nl
P2093
P2860
P356
P1476
Restoring the procofactor stat ...... ntation with B-domain peptides
@en
P2093
Matthew W Bunce
Rodney M Camire
Sriram Krishnaswamy
P2860
P304
30151-30160
P356
10.1074/JBC.M113.506840
P407
P50
P577
2013-09-06T00:00:00Z