Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
about
Novel therapeutic strategies for multiple myelomaIdentification of candidate genes for myeloma-induced osteocyte death based on microarray dataTCRP1 expression is associated with platinum sensitivity in human lung and ovarian cancer cells.A FKBP5 mutation is associated with Paget's disease of bone and enhances osteoclastogenesis.eIF2α signaling regulates ischemic osteonecrosis through endoplasmic reticulum stressImpaired bone homeostasis in amyotrophic lateral sclerosis mice with muscle atrophy.Ethanolic extract of Schizonepeta tenuifolia attenuates osteoclast formation and activation in vitro and protects against lipopolysaccharide-induced bone loss in vivo.Dihydroartemisinin prevents breast cancer-induced osteolysis via inhibiting both breast caner cells and osteoclasts.Dissecting the multiple myeloma-bone microenvironment reveals new therapeutic opportunitiesMethyl Gallate Inhibits Osteoclast Formation and Function by Suppressing Akt and Btk-PLCγ2-Ca2+ Signaling and Prevents Lipopolysaccharide-Induced Bone Loss.Management of bone disease in multiple myeloma.AKT as a therapeutic target in multiple myeloma.MK2206 enhances the cytocidal effects of bufalin in multiple myeloma by inhibiting the AKT/mTOR pathway.Molecular mechanisms, current management and next generation therapy in myeloma bone disease.Targeting leiomyomas with all-trans-retinoic acid at phosphoinositide 3-kinase pathway suppression: Effective roles of β-catenin and of signaling interactions.The blocking of uPAR suppresses lipopolysaccharide-induced inflammatory osteoclastogenesis and the resultant bone loss through attenuation of integrin β3/Akt pathwayuPA-derived peptide, Å6 is involved in the suppression of lipopolysaccaride-promoted inflammatory osteoclastogenesis and the resultant bone loss.Myelomatous plasma cells display an aberrant gene expression pattern similar to that observed in normal memory B cells.
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Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 04 September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
@en
Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
@nl
type
label
Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
@en
Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
@nl
prefLabel
Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
@en
Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
@nl
P2093
P2860
P356
P1476
Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.
@en
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G David Roodman
Guozhi Xiao
Hanjie Niu
Hee-Jeong Im
Huiling Cao
Judith L Anderson
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P304
30399-30410
P356
10.1074/JBC.M113.469973
P407
P577
2013-09-04T00:00:00Z