Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. - Wikidata - wikimedia - TriplyDB

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

http://www.wikidata.org/entity/Q37234638

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Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?To wake up cancer stem cells, or to let them sleep, that is the question Targeting the leukemia-stroma interaction in acute myeloid leukemia: rationale and latest evidence A hostel for the hostile: the bone marrow niche in hematologic neoplasms Advances in understanding the leukaemia microenvironment Stem cell competition: finding balance in the niche Targeting tumor-stromal interactions in bone metastasis Animal models of leukemia: any closer to the real thing?Role of Microenvironment in Resistance to Therapy in AML Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging Overexpression of MN1 confers resistance to chemotherapy, accelerates leukemia onset, and suppresses p53 and Bim induction Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosis MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism Translating leukemia stem cells into the clinical setting: Harmonizing the heterogeneity.Sphingosine-1-Phosphate Receptor-3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche.MicroRNA-9 plays a role in interleukin-10-mediated expression of E-cadherin in acute myelogenous leukemia cells The hematopoietic stem cell niche.The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma.Inhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinoma Challenges in treating older patients with acute myeloid leukemia.Chemokine signaling in cancer: Implications on the tumor microenvironment and therapeutic targeting Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML The Biology and Targeting of FLT3 in Pediatric Leukemia.Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs.A designed peptide targeting CXCR4 displays anti-acute myelocytic leukemia activity in vitro and in vivo.AMD3100 improves ovariectomy-induced osteoporosis in mice by facilitating mobilization of hematopoietic stem/progenitor cells.CD34⁺/CD38⁻ acute myelogenous leukemia cells aberrantly express CD82 which regulates adhesion and survival of leukemia stem cells.Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.Plerixafor is superior to conventional chemotherapy for first-line stem cell mobilisation, and is effective even in heavily pretreated patients The CXCR4 Antagonist AMD3100 Has Dual Effects on Survival and Proliferation of Myeloma Cells In Vitro.Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition.The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway.Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner.Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison.The intricate role of CXCR4 in cancer.

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Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

http://www.wikidata.org/entity/Q37234638

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 02 December 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Chemosensitization of acute my ...... the CXCR4 antagonist AMD3100.

@en

Chemosensitization of acute myeloid leukemia

@nl

type

label

Chemosensitization of acute my ...... the CXCR4 antagonist AMD3100.

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Chemosensitization of acute myeloid leukemia

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prefLabel

Chemosensitization of acute my ...... the CXCR4 antagonist AMD3100.

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Chemosensitization of acute myeloid leukemia

@nl

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BLOOD-2008-06-162123

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Chemosensitization of acute my ...... y the CXCR4 antagonist AMD3100

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Bruno Nervi

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David Piwnica-Worms

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Gary Bridger

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John F DiPersio

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Julie K Ritchey

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Julie L Prior

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Matthew S Holt

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Michael P Rettig

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Pablo Ramirez

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Timothy J Ley

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P2860

Cytokines and hematopoietic stem cell mobilization

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

p27(kip1) acts as a downstream effector of and is coexpressed with the beta1C integrin in prostatic adenocarcinoma

Nucleoside analogues: mechanisms of drug resistance and reversal strategies.

The use of AMD3100 plus G-CSF for autologous hematopoietic progenitor cell mobilization is superior to G-CSF alone.

Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia.

Essential role of stromally induced hedgehog signaling in B-cell malignancies.

G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells.

Spying on cancer: molecular imaging in vivo with genetically encoded reporters.

The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood.

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