Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion. - Wikidata - wikimedia - TriplyDB

Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

http://www.wikidata.org/entity/Q37236329

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Physiologic characterization of type 2 diabetes-related loci Novel phenotypes of prediabetes?Regulation of Intestinal Glucose Absorption by Ion Channels and Transporters Incretin physiology and pathophysiology from an Asian perspective Non-alcoholic fatty liver disease and type 2 diabetes mellitus: the liver disease of our age?Differential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expression Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp Evaluation of fasting state-/oral glucose tolerance test-derived measures of insulin release for the detection of genetically impaired β-cell function KCNQ1, a susceptibility gene for type 2 diabetes.Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus.Allele summation of diabetes risk genes predicts impaired glucose tolerance in female and obese individuals.Patient profiling in diabetes and role of canagliflozin.Polymorphisms of GLP-1 receptor gene and response to GLP-1 analogue in patients with poorly controlled type 2 diabetes.Obesity and diabetes genetic variants associated with gestational weight gain Hyperinsulinism and diabetes: genetic dissection of beta cell metabolism-excitation coupling in mice The rs2237892 Polymorphism in KCNQ1 Influences Gestational Diabetes Mellitus and Glucose Levels: A Case-Control Study and Meta-Analysis Chromanol 293B, an inhibitor of KCNQ1 channels, enhances glucose-stimulated insulin secretion and increases glucagon-like peptide-1 level in mice Association Between KCNQ1 Genetic Variants and Type 2 Diabetes in the Uyghur Population.Impaired secretion of glucagon-like peptide 1 during oral glucose tolerance test in patients with newly diagnosed type 2 diabetes mellitus.Polymorphisms in Four Genes (KCNQ1 rs151290, KLF14 rs972283, GCKR rs780094 and MTNR1B rs10830963) and Their Correlation with Type 2 Diabetes Mellitus in Han Chinese in Henan Province, China Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes.Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium.Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis.Pharmacogenetics of oral antidiabetic drugs.Maternal genotype and gestational diabetes Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes.Molecular mechanisms underlying nutrient-stimulated incretin secretion.Impairment of GLP1-induced insulin secretion: role of genetic background, insulin resistance and hyperglycaemia.Ghrelin, the proglucagon-derived peptides and peptide YY in nutrient homeostasis.Pancreatic gene variants potentially associated with dipeptidyl peptidase-4 inhibitor treatment response in Type 2 diabetes.Genetics of drug response in type 2 diabetes.Pharmacogenetic aspects of the treatment of Type 2 diabetes with the incretin effect enhancers.Personalized management of hyperglycemia in type 2 diabetes: reflections from a Diabetes Care Editors' Expert Forum.A single nucleotide polymorphism in KCNQ1 is associated with susceptibility to diabetic nephropathy in japanese subjects with type 2 diabetes.Type 2 diabetes associated variants of KCNQ1 strongly confer the risk of cardiovascular disease among the Saudi Arabian population.Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion.Variation in KCNQ1 is associated with therapeutic response to sulphonylureas.Electrical activity-triggered glucagon-like peptide-1 secretion from primary murine L-cells.

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Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

http://www.wikidata.org/entity/Q37236329

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 14 April 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Association of type 2 diabetes ...... ncretin and insulin secretion.

@en

Association of type 2 diabetes ...... ncretin and insulin secretion.

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type

label

Association of type 2 diabetes ...... ncretin and insulin secretion.

@en

Association of type 2 diabetes ...... ncretin and insulin secretion.

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prefLabel

Association of type 2 diabetes ...... ncretin and insulin secretion.

@en

Association of type 2 diabetes ...... ncretin and insulin secretion.

@nl

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Association of type 2 diabetes ...... ncretin and insulin secretion.

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Andreas Fritsche

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Fausto Machicao

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Günther Silbernagel

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Karsten Müssig

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Kerstin Kirchhoff

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Konstantinos Kantartzis

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Martina Guthoff

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Silke A Schäfer

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P2860

Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo

Colocalization of KCNQ1/KCNE channel subunits in the mouse gastrointestinal tract

A genome-wide association study identifies novel risk loci for type 2 diabetes

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells

KCNQ1-dependent transport in renal and gastrointestinal epithelia

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

Molecular biology and the prolonged QT syndromes.

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1715-1720

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scholarly article

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10.2337/DB08-1589

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7

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58

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Jens Juul Holst

Baptist Gallwitz

Hans-Ulrich Häring

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2009-04-14T00:00:00Z

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24278011

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19366866

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type-2 diabetes

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2699873

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