Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach - Wikidata - wikimedia - TriplyDB

Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach

Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach

http://www.wikidata.org/entity/Q37237411

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The role of Snail in prostate cancer The cancer stem cell niche--there goes the neighborhood?Galiellalactone inhibits stem cell-like ALDH-positive prostate cancer cells Pathobiological implications of the expression of EGFR, pAkt, NF-κB and MIC-1 in prostate cancer stem cells and their progenies Independent component analysis: mining microarray data for fundamental human gene expression modules Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor-initiating cells.Characterisation of a novel cell line (CSQT-2) with high metastatic activity derived from portal vein tumour thrombus of hepatocellular carcinoma.Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies.The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers.Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation.Frequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.Animal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells.Synergistic effects of the sesquiterpene lactone, EPD, with cisplatin and paclitaxel in ovarian cancer cells.Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis.New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells.Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.Increased chemosensitivity via targeting testicular nuclear receptor 4 (TR4)-Oct4-interleukin 1 receptor antagonist (IL1Ra) axis in prostate cancer CD133+ stem/progenitor cells to battle prostate cancer Cryptotanshinone targets tumor-initiating cells through down-regulation of stemness genes expression.Discovery of potent parthenolide-based antileukemic agents enabled by late-stage P450-mediated C-H functionalization.In human retinoblastoma Y79 cells okadaic acid-parthenolide co-treatment induces synergistic apoptotic effects, with PTEN as a key player.Mechanisms of Chromosome Congression during Mitosis.Towards novel paradigms for cancer therapy.Sesquiterpene lactones: adverse health effects and toxicity mechanisms.The Multifaceted Roles of STAT3 Signaling in the Progression of Prostate Cancer.Anticancer activity profiling of parthenolide analogs generated via P450-mediated chemoenzymatic synthesis.Elimination of ALDH+ breast tumor initiating cells by docosahexanoic acid and/or gamma tocotrienol through SHP-1 inhibition of Stat3 signaling.SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin.Inhibition of Myb-dependent gene expression by the sesquiterpene lactone mexicanin-I.Cell context-dependent activities of parthenolide in primary and metastatic melanoma cells Pharmacological targeting of glucose-6-phosphate dehydrogenase in human erythrocytes by Bay 11-7082, parthenolide and dimethyl fumarate.Cancer complementary and alternative medicine research at the US National Cancer Institute.Targeting CDK6 and BCL2 exploits the "MYB addiction" of Ph+ acute lymphoblastic leukemia.The plant sesquiterpene lactone parthenoide inhibits Wnt/β-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1.Parthenolide facilitates apoptosis and reverses drug-resistance of human gastric carcinoma cells by inhibiting the STAT3 signaling pathway.Platinum-catalyzed cycloisomerizations of a common enyne: a divergent entry to cyclopropane sesquiterpenoids. Formal synthesis of sarcandralactone A.Synergistic anti-cancer effects of epigenetic drugs on medulloblastoma cells.Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation.Biological Activity of Flavonoids and Rare Sesquiterpene Lactones Isolated From L Synthesis and biological evaluation of dithiocarbamate esters of parthenolide as potential anti-acute myelogenous leukaemia agents Isolation and Structural Characterization of Bioactive Molecules on Prostate Cancer from Mayan Traditional Medicinal Plants

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Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach

http://www.wikidata.org/entity/Q37237411

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Effects of the sesquiterpene l ...... d molecular profiling approach

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Effects of the sesquiterpene l ...... molecular profiling approach.

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type

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Effects of the sesquiterpene l ...... d molecular profiling approach

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Effects of the sesquiterpene l ...... molecular profiling approach.

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Effects of the sesquiterpene l ...... d molecular profiling approach

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Effects of the sesquiterpene l ...... molecular profiling approach.

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Effects of the sesquiterpene l ...... d molecular profiling approach

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Brian T Kawasaki

http://www.w3.org/2001/XMLSchema#string

Elaine M Hurt

http://www.w3.org/2001/XMLSchema#string

John A Milner

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Maria Ana Duhagon

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William L Farrar

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Young S Kim

http://www.w3.org/2001/XMLSchema#string

P2860

Androgen induction of the androgen receptor coactivator four and a half LIM domain protein-2: evidence for a role for serum response factor in prostate cancer

Identification of growth factor independent-1 (GFI1) as a repressor of 25-hydroxyvitamin D 1-alpha hydroxylase (CYP27B1) gene expression in human prostate cancer cells

Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

Clinical and experimental progression of a new model of human prostate cancer and therapeutic approach

Feverfew: weeding out the root of leukaemia

Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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827-837

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scholarly article

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10.1002/PROS.20931

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8

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69

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Madhuri Kalathur

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2009-06-01T00:00:00Z

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23995334

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19204913

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2700306

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