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Glycosylation of fibroblast growth factor receptor 4 is a key regulator of fibroblast growth factor 19-mediated down-regulation of cytochrome P450 7A1Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlothoThe alternatively spliced acid box region plays a key role in FGF receptor autoinhibitionKlotho and agingFibroblast growth factor signaling in skeletal development and diseaseHomodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular MatrixPlasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1A potential link between phosphate and aging--lessons from Klotho-deficient miceFunctional diversity of fibroblast growth factors in bone formationFGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.The Fibroblast Growth Factor signaling pathwayPhosphate sensing.Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms.Klotho and the aging processMolecular regulation of phosphate metabolism by fibroblast growth factor-23-klotho systemThe effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells.Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23.Klotho locus, metabolic traits, and serum hemoglobin in hospitalized older patients: a genetic association analysis.The role of Klotho in energy metabolism.The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS.Lean phenotype and resistance to diet-induced obesity in vitamin D receptor knockout mice correlates with induction of uncoupling protein-1 in white adipose tissue.MicroRNA-34a and Impaired FGF19/21 Signaling in ObesityExpression profile and overexpression outcome indicate a role for βKlotho in skeletal muscle fibro/adipogenesis.Klotho variants and chronic hemodialysis mortalityDisorders of phosphate homeostasis and tissue mineralisation.Digestive physiology of the pig symposium: intestinal bile acid sensing is linked to key endocrine and metabolic signaling pathways.Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease.Impact of new-generation lipid emulsions on cellular mechanisms of parenteral nutrition-associated liver disease.An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities.Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.Mechanisms of FGF gradient formation during embryogenesis.Current disease modifying approaches to treat Parkinson's disease.FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process.Fibroblast Growth Factors in the Gastrointestinal Tract: Twists and Turns.Computational drill down on FGF1-heparin interactions through methodological evaluation.Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation.FGF21 as an Endocrine Regulator in Lipid Metabolism: From Molecular Evolution to Physiology and PathophysiologyShort-term dietary phosphate restriction up-regulates ileal fibroblast growth factor 15 gene expression in mice.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 07 August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Endocrine FGFs and Klothos: emerging concepts.
@en
Endocrine FGFs and Klothos: emerging concepts.
@nl
type
label
Endocrine FGFs and Klothos: emerging concepts.
@en
Endocrine FGFs and Klothos: emerging concepts.
@nl
prefLabel
Endocrine FGFs and Klothos: emerging concepts.
@en
Endocrine FGFs and Klothos: emerging concepts.
@nl
P1476
Endocrine FGFs and Klothos: emerging concepts.
@en
P2093
Makoto Kuro-o
P304
P356
10.1016/J.TEM.2008.06.002
P577
2008-08-07T00:00:00Z