Familial parkinsonism: study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes.
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TDP-43 pathology in a patient carrying G2019S LRRK2 mutation and a novel p.Q124E MAPTThe genetics and neuropathology of Parkinson's diseaseThe role of the LRRK2 gene in ParkinsonismIs inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease?First neuropathological description of a patient with Parkinson's disease and LRRK2 p.N1437H mutationIdentification of a Japanese family with LRRK2 p.R1441G-related Parkinson's diseaseLeucine-rich repeat kinase 2 gene-associated disease: redefining genotype-phenotype correlationThe I2020T Leucine-rich repeat kinase 2 transgenic mouse exhibits impaired locomotive ability accompanied by dopaminergic neuron abnormalitiesNeurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation.α-Synuclein oligomers and clinical implications for Parkinson disease.Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions.Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusionsCell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps.The neuropathology of genetic Parkinson's disease.Molecular determinants of selective dopaminergic vulnerability in Parkinson's disease: an update.Leucine-Rich Repeat Kinase (LRRK2) Genetics and Parkinson's Disease.I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway.Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies.Multisystem Lewy body disease and the other parkinsonian disorders.Reduced LRRK2 in association with retromer dysfunction in post-mortem brain tissue from LRRK2 mutation carriers.Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.Neuropathology of genetic synucleinopathies with parkinsonism: Review of the literature.Alterations in the reduced pteridine contents in the cerebrospinal fluids of LRRK2 mutation carriers and patients with Parkinson's disease.Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations
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P2860
Familial parkinsonism: study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Familial parkinsonism: study o ...... le clinicopathologic outcomes.
@en
Familial parkinsonism: study of original Sagamihara PARK8
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type
label
Familial parkinsonism: study o ...... le clinicopathologic outcomes.
@en
Familial parkinsonism: study of original Sagamihara PARK8
@nl
prefLabel
Familial parkinsonism: study o ...... le clinicopathologic outcomes.
@en
Familial parkinsonism: study of original Sagamihara PARK8
@nl
P2093
P2860
P1476
Familial parkinsonism: study o ...... le clinicopathologic outcomes.
@en
P2093
A Jon Stoessl
Hisayuki Kowa
Kazuko Hasegawa
Saburo Yagishita
Teruo Yokoyama
P2860
P304
P356
10.1016/J.PARKRELDIS.2008.07.010
P577
2008-09-18T00:00:00Z