Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death.
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Kainic Acid-Induced Excitotoxicity Experimental Model: Protective Merits of Natural Products and Plant ExtractsLovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome.The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.Ginseng Rb fraction protects glia, neurons and cognitive function in a rat model of neurodegenerationAdministration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy.Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis.Lovastatin modulates glycogen synthase kinase-3β pathway and inhibits mossy fiber sprouting after pilocarpine-induced status epilepticus.Molecular mechanisms underlying the effects of statins in the central nervous system.Kainic Acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines.Novel applications of statins for bone regenerationMolecular contributions to neurovascular unit dysfunctions after brain injuries: lessons for target-specific drug development.Pharmacoresistant Epilepsy: A Current Update on Non-Conventional Pharmacological and Non-Pharmacological InterventionsExploring novel AEDs from drugs used for treatment of non-epileptic disorders.Identifying new antiepileptic drugs through genomics-based drug repurposing.The beneficial effects of HMG-CoA reductase inhibitors in the processes of neurodegeneration.Anticonvulsant and Antioxidant Effects of Pitavastatin Against Pentylenetetrazol-Induced Kindling in Mice.Augmentation of fluoxetine with lovastatin for treating major depressive disorder, a randomized double-blind placebo controlled-clinical trial.The protective effect of myo-inositol on hippocamal cell loss and structural alterations in neurons and synapses triggered by kainic acid-induced status epilepticus.Statin treatment may lower the risk of postradiation epilepsy in patients with nasopharyngeal carcinoma.Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1-40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems.Protective effects of some statins on epileptogenesis and depressive-like behavior in WAG/Rij rats, a genetic animal model of absence epilepsy.The involvement of nitric oxide in the anti-seizure effect of acute atorvastatin treatment in mice.The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus.Differential effects of atorvastatin treatment and withdrawal on pentylenetetrazol-induced seizures.Hydroalcoholic extract of Emblica officinalis protects against kainic acid-induced status epilepticus in rats: evidence for an antioxidant, anti-inflammatory, and neuroprotective intervention.Atorvastatin treatment during epileptogenesis in a rat model for temporal lobe epilepsy.Rosmarinic acid exerts a neuroprotective effect in the kainate rat model of temporal lobe epilepsy: Underlying mechanisms.Atorvastatin pretreatment attenuates kainic acid-induced hippocampal neuronal death via regulation of lipocalin-2-associated neuroinflammation.RNAseq analysis of hippocampal microglia after kainic acid-induced seizures.The Effect of Statins in Epilepsy: A Systematic Review
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Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 June 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Statin inhibits kainic acid-in ...... on and hippocampal cell death.
@en
Statin inhibits kainic acid-in ...... on and hippocampal cell death.
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type
label
Statin inhibits kainic acid-in ...... on and hippocampal cell death.
@en
Statin inhibits kainic acid-in ...... on and hippocampal cell death.
@nl
prefLabel
Statin inhibits kainic acid-in ...... on and hippocampal cell death.
@en
Statin inhibits kainic acid-in ...... on and hippocampal cell death.
@nl
P2093
P2860
P1433
P1476
Statin inhibits kainic acid-in ...... on and hippocampal cell death.
@en
P2093
Avtar K Singh
Inderjit Singh
Je-Seong Won
Jin-Koo Lee
P2860
P304
P356
10.1016/J.NEULET.2008.05.112
P407
P577
2008-06-06T00:00:00Z