alpha-Tocopheryl succinate and derivatives mediate the transcriptional repression of androgen receptor in prostate cancer cells by targeting the PP2A-JNK-Sp1-signaling axis.
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Quantitative iTRAQ LC-MS/MS Proteomics Reveals Transcription Factor Crosstalk and Regulatory Networks in Hypopharyngeal Squamous Cell CarcinomaHistone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases.The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells.Potent inhibitory effect of δ-tocopherol on prostate cancer cells cultured in vitro and grown as xenograft tumors in vivo.Promoter hypomethylation results in increased expression of protein phosphatase 2A in T cells from patients with systemic lupus erythematosus.Cardamonin Suppresses TGF-β1-Induced Epithelial Mesenchymal Transition via Restoring Protein Phosphatase 2A ExpressionPP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21.Mechanism of differentiation-enhanced photodynamic therapy for cancer: upregulation of coproporphyrinogen oxidase by C/EBP transcription factors.PP2A-Mediated Anticancer Therapy.Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target.miR-222 attenuates cisplatin-induced cell death by targeting the PPP2R2A/Akt/mTOR Axis in bladder cancer cellsAll roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.Inhibition of Notch1 signaling overcomes resistance to the death ligand Trail by specificity protein 1-dependent upregulation of death receptor 5.Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets.Total syntheses of the histone deacetylase inhibitors largazole and 2-epi-largazole: application of N-heterocyclic carbene mediated acylations in complex molecule synthesis.Passive mechanical forces upregulate the fast myosin heavy chain IId/x via integrin and p38 MAP kinase activation in a primary muscle cell culture.PP2A as the Main Node of Therapeutic Strategies and Resistance Reversal in Triple-Negative Breast Cancer.Therapeutic Targeting of PP2A.PP2A inhibition as a novel therapeutic target in castration-resistant prostate cancer.
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P2860
alpha-Tocopheryl succinate and derivatives mediate the transcriptional repression of androgen receptor in prostate cancer cells by targeting the PP2A-JNK-Sp1-signaling axis.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 06 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
alpha-Tocopheryl succinate and ...... e PP2A-JNK-Sp1-signaling axis.
@en
alpha-Tocopheryl succinate and ...... e PP2A-JNK-Sp1-signaling axis.
@nl
type
label
alpha-Tocopheryl succinate and ...... e PP2A-JNK-Sp1-signaling axis.
@en
alpha-Tocopheryl succinate and ...... e PP2A-JNK-Sp1-signaling axis.
@nl
prefLabel
alpha-Tocopheryl succinate and ...... e PP2A-JNK-Sp1-signaling axis.
@en
alpha-Tocopheryl succinate and ...... e PP2A-JNK-Sp1-signaling axis.
@nl
P2093
P2860
P356
P1433
P1476
alpha-Tocopheryl succinate and ...... e PP2A-JNK-Sp1-signaling axis.
@en
P2093
Ching-Shih Chen
Dasheng Wang
Hsiao-Ching Chuang
Po-Hsien Huang
Samuel K Kulp
P2860
P304
P356
10.1093/CARCIN/BGP112
P407
P577
2009-05-06T00:00:00Z