Unravelling the tumor-suppressive functions of FOXO proteins.
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Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradationSirtuin 1 and sirtuin 3: physiological modulators of metabolismWnt activation protects against neomycin-induced hair cell damage in the mouse cochleaCell-nonautonomous signaling of FOXO/DAF-16 to the stem cells of Caenorhabditis elegansFrom estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosisResveratrol induces growth arrest and apoptosis through activation of FOXO transcription factors in prostate cancer cellsDiscovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic ShuttlingROS function in redox signaling and oxidative stressT-Type Ca2+ Channel Inhibition Sensitizes Ovarian Cancer to Carboplatin.Resveratrol enhances antitumor activity of TRAIL in prostate cancer xenografts through activation of FOXO transcription factor.Bimodal regulation of FoxO3 by AKT and 14-3-3BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cellsFOXO1 controls thyroid cell proliferation in response to TSH and IGF-I and is involved in thyroid tumorigenesis.FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in miceUSP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy.Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT.The cancer theory of pulmonary arterial hypertension.Increased FOXM1 expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence.Constitutive phosphorylation of the FOXO1 transcription factor in gastric cancer cells correlates with microvessel area and the expressions of angiogenesis-related molecules.Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescenceFoxo1 regulates Dbh expression and the activity of the sympathetic nervous system in vivo.Mutation spectrum in human colorectal cancers and potential functional relevance.Identification of a mechanism underlying regulation of the anti-angiogenic forkhead transcription factor FoxO1 in cultured endothelial cells and ischemic muscle.Sorting out functions of sirtuins in cancerPLZF mediates the PTEN/AKT/FOXO3a signaling in suppression of prostate tumorigenesis.FHIT gene expression is repressed by mitogenic signaling through the PI3K/AKT/FOXO pathway.Sequence-based design of bioactive small molecules that target precursor microRNAs.mTOR inhibition induces EGFR feedback activation in association with its resistance to human pancreatic cancer.EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment.The PAX3-FOXO1 fusion protein present in rhabdomyosarcoma interferes with normal FOXO activity and the TGF-β pathway.MiR-21: an environmental driver of malignant melanoma?Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER.Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways.Helicobacter pylori-associated regulation of forkhead transcription factors FoxO1/3a in human gastric cellsMicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathwayFOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expressionThe B-cell antigen receptor integrates adaptive and innate immune signalsForkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL).Zebrafish foxo3b Negatively Regulates Antiviral Response through Suppressing the Transactivity of irf3 and irf7.Microbes-induced EMT at the crossroad of inflammation and cancer.
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P2860
Unravelling the tumor-suppressive functions of FOXO proteins.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Unravelling the tumor-suppressive functions of FOXO proteins.
@en
Unravelling the tumor-suppressive functions of FOXO proteins.
@nl
type
label
Unravelling the tumor-suppressive functions of FOXO proteins.
@en
Unravelling the tumor-suppressive functions of FOXO proteins.
@nl
prefLabel
Unravelling the tumor-suppressive functions of FOXO proteins.
@en
Unravelling the tumor-suppressive functions of FOXO proteins.
@nl
P1476
Unravelling the tumor-suppressive functions of FOXO proteins.
@en
P2093
Boudewijn M T Burgering
P304
P356
10.1016/J.TCB.2008.07.004
P577
2008-08-18T00:00:00Z