LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development.
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Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunitiesThe LRIG family: enigmatic regulators of growth factor receptor signaling.LRIG1 as a potential novel marker for neoplastic transformation in ocular surface squamous neoplasiaLRIG and cancer prognosis.LRIG1 enhances the radiosensitivity of radioresistant human glioblastoma U251 cells via attenuation of the EGFR/Akt signaling pathway.Clonal Dynamics Reveal Two Distinct Populations of Basal Cells in Slow-Turnover Airway Epithelium.LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells.An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.Beyond the niche: tissue-level coordination of stem cell dynamics.LRIG1 enhances chemosensitivity by modulating BCL-2 expression and receptor tyrosine kinase signaling in glioma cells.LRIG1 is a prognostic biomarker in non-small cell lung cancer.Downregulation of LRIG2 expression inhibits angiogenesis of glioma via EGFR/VEGF-A pathway.The epidermis comprises autonomous compartments maintained by distinct stem cell populations.A protein interaction network centered on leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) regulates growth factor receptors.Lrig1 is a haploinsufficient tumor suppressor gene in malignant glioma.
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P2860
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on March 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
LRIG1 regulates cadherin-depen ...... us cell carcinoma development.
@en
LRIG1 regulates cadherin-depen ...... us cell carcinoma development.
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type
label
LRIG1 regulates cadherin-depen ...... us cell carcinoma development.
@en
LRIG1 regulates cadherin-depen ...... us cell carcinoma development.
@nl
prefLabel
LRIG1 regulates cadherin-depen ...... us cell carcinoma development.
@en
LRIG1 regulates cadherin-depen ...... us cell carcinoma development.
@nl
P2093
P2860
P50
P356
P1476
LRIG1 regulates cadherin-depen ...... ous cell carcinoma development
@en
P2093
Adam Giangreco
Andrew G Nicholson
Bernadette Carroll
David Endesfelder
Jeremy P George
Krishna Kolluri
Maik Kschischo
Mary Falzon
Nicholas Hamilton
P2860
P304
P356
10.1002/PATH.4148
P577
2013-03-01T00:00:00Z