Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow
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Laminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activationUnspliced X-box-binding protein 1 (XBP1) protects endothelial cells from oxidative stress through interaction with histone deacetylase 3Exploiting the Pleiotropic Antioxidant Effects of Established Drugs in Cardiovascular DiseaseReview article: carbon monoxide in gastrointestinal physiology and its potential in therapeuticsStatins decrease neuroinflammation and prevent cognitive impairment after cerebral malariaStress-activated cap'n'collar transcription factors in aging and human diseasePharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malariaDiet induced mild hypercholesterolemia in pigs: local and systemic inflammation, effects on vascular injury - rescue by high-dose statin treatmentKeap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals.Complement-mediated injury and protection of endothelium: lessons from atypical haemolytic uraemic syndromeEffects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectivesHeme oxygenase in the regulation of vascular biology: from molecular mechanisms to therapeutic opportunities.Effect of rosuvastatin on hyperuricemic rats and the protective effect on endothelial dysfunctionThe role of blood flow in determining the sites of atherosclerotic plaques.Characterization of partial ligation-induced carotid atherosclerosis model using dual-modality molecular imaging in ApoE knock-out mice"Go with the flow": how Krüppel-like factor 2 regulates the vasoprotective effects of shear stress.Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy.Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension.Induction and functional significance of the heme oxygenase system in pathological shear stress in vivo.Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption.Flow cessation triggers endothelial dysfunction during organ cold storage conditions: strategies for pharmacologic interventionSildenafil stimulates the expression of gaseous monoxide-generating enzymes in vascular smooth muscle cells via distinct signaling pathwaysHeme oxygenase-1-derived bilirubin counteracts HIV protease inhibitor-mediated endothelial cell dysfunctionVascular Protective Role of Samul-Tang in HUVECs: Involvement of Nrf2/HO-1 and NO.Contributions of the Ah receptor to bilirubin homeostasis and its antioxidative and atheroprotective functions.Protective role of heme oxygenase-1 against inflammation in atherosclerosis.High cholesterol diet effects on ischemia-reperfusion injury of the heart.Cytoprotective signaling and gene expression in endothelial cells and macrophages-lessons for atherosclerosis.Biological and Physical Factors Involved in the Maturation of Arteriovenous Fistula for Hemodialysis.hnRNPK-regulated PTOV1-AS1 modulates heme oxygenase-1 expression via miR-1207-5p.Effects of shear stress on endothelial cells: go with the flow.Biomechanical factors in atherosclerosis: mechanisms and clinical implications.Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line.Active NF-E2-related factor (Nrf2) contributes to keep endothelial NO synthase (eNOS) in the coupled state: role of reactive oxygen species (ROS), eNOS, and heme oxygenase (HO-1) levels.Red Yeast Rice Protects Circulating Bone Marrow-Derived Proangiogenic Cells against High-Glucose-Induced Senescence and Oxidative Stress: The Role of Heme Oxygenase-1.Implantation of a carotid cuff for triggering shear-stress induced atherosclerosis in mice.Oscillatory flow accelerates autocrine signaling due to nonlinear effect of convection on receptor-related actions.Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats.Statins prevent cervical remodeling, myometrial contractions and preterm labor through a mechanism that involves hemoxygenase-1 and complement inhibition.
P2860
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P2860
Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 19 May 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Induction of the cytoprotectiv ...... and impaired by disturbed flow
@en
Induction of the cytoprotectiv ...... nd impaired by disturbed flow.
@nl
type
label
Induction of the cytoprotectiv ...... and impaired by disturbed flow
@en
Induction of the cytoprotectiv ...... nd impaired by disturbed flow.
@nl
prefLabel
Induction of the cytoprotectiv ...... and impaired by disturbed flow
@en
Induction of the cytoprotectiv ...... nd impaired by disturbed flow.
@nl
P2093
P2860
P356
P1476
Induction of the cytoprotectiv ...... and impaired by disturbed flow
@en
P2093
Andrea Bauer
Dorian O Haskard
Elaine A Lidington
Faisal Ali
Joseph J Boyle
Justin C Mason
Kersti Karu
Mustafa Zakkar
Shahir S Hamdulay
P2860
P304
18882-18892
P356
10.1074/JBC.M109.009886
P407
P577
2009-05-19T00:00:00Z