Identification of novel SHPS-1-associated proteins and their roles in regulation of insulin-like growth factor-dependent responses in vascular smooth muscle cells.
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Structure and Biological Importance of the Spn1-Spt6 Interaction, and Its Regulatory Role in Nucleosome BindingCrystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 DomainInsulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells.Advantages of mRNA display selections over other selection techniques for investigation of protein-protein interactions.PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival.Hyperglycemia-induced p66shc inhibits insulin-like growth factor I-dependent cell survival via impairment of Src kinase-mediated phosphoinositide-3 kinase/AKT activation in vascular smooth muscle cells.IGF-I stimulates cooperative interaction between the IGF-I receptor and CSK homologous kinase that regulates SHPS-1 phosphorylation in vascular smooth muscle cells.The coordinate cellular response to insulin-like growth factor-I (IGF-I) and insulin-like growth factor-binding protein-2 (IGFBP-2) is regulated through vimentin binding to receptor tyrosine phosphatase β (RPTPβ)Signal regulatory protein-α protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signalingHyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells.Insulin-like growth factor (IGF) binding protein 2 functions coordinately with receptor protein tyrosine phosphatase β and the IGF-I receptor to regulate IGF-I-stimulated signaling.Cleavage of Signal Regulatory Protein α (SIRPα) Enhances Inflammatory Signaling.Recruitment of Nox4 to a plasma membrane scaffold is required for localized reactive oxygen species generation and sustained Src activation in response to insulin-like growth factor-I.
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Identification of novel SHPS-1-associated proteins and their roles in regulation of insulin-like growth factor-dependent responses in vascular smooth muscle cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Identification of novel SHPS-1 ...... vascular smooth muscle cells.
@en
Identification of novel SHPS-1 ...... vascular smooth muscle cells.
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type
label
Identification of novel SHPS-1 ...... vascular smooth muscle cells.
@en
Identification of novel SHPS-1 ...... vascular smooth muscle cells.
@nl
prefLabel
Identification of novel SHPS-1 ...... vascular smooth muscle cells.
@en
Identification of novel SHPS-1 ...... vascular smooth muscle cells.
@nl
P2093
P2860
P1476
Identification of novel SHPS-1 ...... vascular smooth muscle cells.
@en
P2093
David R Clemmons
Xinchun Shen
Yashwanth Radhakrishnan
P2860
P304
P356
10.1074/MCP.M800543-MCP200
P577
2009-03-18T00:00:00Z