Hyperglycemia regulates RUNX2 activation and cellular wound healing through the aldose reductase polyol pathway.
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Intensive versus conventional glycaemic control for treating diabetic foot ulcersIntensive versus conventional glycaemic control for treating diabetic foot ulcersApplication of VEGFA and FGF-9 enhances angiogenesis, osteogenesis and bone remodeling in type 2 diabetic long bone regenerationCancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motilityRestoration of Nrf2 Signaling Normalizes the Regenerative Niche.NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does notInpatient HbA1c testing: a prospective observational study.The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer CellsRunx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells.A quantitative assay to study protein:DNA interactions, discover transcriptional regulators of gene expression, and identify novel anti-tumor agents.Regulation of RUNX2 transcription factor-DNA interactions and cell proliferation by vitamin D3 (cholecalciferol) prohormone activity.Damaging effects of hyperglycemia on cardiovascular function: spotlight on glucose metabolic pathways.Glucose-activated RUNX2 phosphorylation promotes endothelial cell proliferation and an angiogenic phenotypeHyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells.Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo.Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity.Palmitic acid dysregulates the Hippo-YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS-STING-IRF3 signaling mechanism.
P2860
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P2860
Hyperglycemia regulates RUNX2 activation and cellular wound healing through the aldose reductase polyol pathway.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Hyperglycemia regulates RUNX2 ...... dose reductase polyol pathway.
@en
Hyperglycemia regulates RUNX2 ...... dose reductase polyol pathway.
@nl
type
label
Hyperglycemia regulates RUNX2 ...... dose reductase polyol pathway.
@en
Hyperglycemia regulates RUNX2 ...... dose reductase polyol pathway.
@nl
prefLabel
Hyperglycemia regulates RUNX2 ...... dose reductase polyol pathway.
@en
Hyperglycemia regulates RUNX2 ...... dose reductase polyol pathway.
@nl
P2093
P2860
P356
P1476
Hyperglycemia regulates RUNX2 ...... dose reductase polyol pathway.
@en
P2093
Antonino Passaniti
David R D'Souza
Jessica Bennett
Kaushal Asrani
Keli J Renoud
Maria Mochin-Peters
Maryann M Salib
Paul Shapiro
Simeon E Goldblum
P2860
P304
17947-17955
P356
10.1074/JBC.M109.002378
P407
P577
2009-04-21T00:00:00Z