Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells.
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Mammalian Krüppel-like factors in health and diseasesEvasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformationHDAC2 phosphorylation-dependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCsKrüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cellsInterruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells.Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathwaysDifferent expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells.Estrogen up-regulates ATBF1 transcription but causes its protein degradation in estrogen receptor-alpha-positive breast cancer cellsMechanisms of transforming growth factor β induced cell cycle arrest in palate developmentMyosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transitionRoles of Klf5 Acetylation in the Self-Renewal and the Differentiation of Mouse Embryonic Stem Cells.Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription.Site-specific acetylation of the proteasome activator REGγ directs its heptameric structure and functions.Oestrogen causes degradation of KLF5 by inducing the E3 ubiquitin ligase EFP in ER-positive breast cancer cells.KLF5 activates microRNA 200 transcription to maintain epithelial characteristics and prevent induced epithelial-mesenchymal transition in epithelial cells.A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).Krüppel-like factors 4 and 5: unity in diversityDNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma.KLF5 promotes cell migration by up-regulating FYN in bladder cancer cells.A pivotal role of Krüppel-like factor 5 in regulation of cancer stem-like cells in hepatocellular carcinoma.Functional and clinical evidence that TAZ is a candidate oncogene in hepatocellular carcinoma.Mechanisms of transcription factor acetylation and consequences in hearts.The changing role of TGFβ in healthy, ageing and osteoarthritic joints.TAZ antagonizes the WWP1-mediated KLF5 degradation and promotes breast cell proliferation and tumorigenesis.Opposing effects of KLF5 on the transcription of MYC in epithelial proliferation in the context of transforming growth factor beta.KLF5 and hhLIM cooperatively promote proliferation of vascular smooth muscle cells.Down-regulation of the klf5-c-Myc interaction due to klf5 phosphorylation mediates resveratrol repressing the caveolin-1 transcription through the PI3K/PKD1/Akt pathway.Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar to Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.HDAC-mediated deacetylation of KLF5 associates with its proteasomal degradation.The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury.Chinese medicine Tongxinluo increases tight junction protein levels by inducing KLF5 expression in microvascular endothelial cells.TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer
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Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 06 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Acetylation of KLF5 alters the ...... induction in epithelial cells.
@en
Acetylation of KLF5 alters the ...... induction in epithelial cells.
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type
label
Acetylation of KLF5 alters the ...... induction in epithelial cells.
@en
Acetylation of KLF5 alters the ...... induction in epithelial cells.
@nl
prefLabel
Acetylation of KLF5 alters the ...... induction in epithelial cells.
@en
Acetylation of KLF5 alters the ...... induction in epithelial cells.
@nl
P2860
P50
P356
P1476
Acetylation of KLF5 alters the ...... induction in epithelial cells.
@en
P2093
Ke-Wen Zhao
P2860
P304
18184-18193
P356
10.1074/JBC.M109.007096
P407
P577
2009-05-06T00:00:00Z