Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition - Wikidata - wikimedia - TriplyDB

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

http://www.wikidata.org/entity/Q37258903

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The notch ligand JAGGED1 as a target for anti-tumor therapy Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.Slug is a direct Notch target required for initiation of cardiac cushion cellularization Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts Differential effects of the HESR/HEY transcription factor family on dopamine transporter reporter gene expression via variable number of tandem repeats Biology of fibroblasts and myofibroblasts Small C-terminal domain phosphatase enhances snail activity through dephosphorylation Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers The epithelial-mesenchymal transition: new insights in signaling, development, and disease Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling Endothelial Transdifferentiation of Tumor Cells Triggered by the Twist1-Jagged1-KLF4 Axis: Relationship between Cancer Stemness and Angiogenesis Kick it up a notch: Notch signaling and kidney fibrosis Circulating Tumor Cells: A Window Into Tumor Development and Therapeutic Effectiveness Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer Impact of notch signaling on inflammatory responses in cardiovascular disorders Notch: a key regulator of tumor angiogenesis and metastasis A role for partial endothelial-mesenchymal transitions in angiogenesis?Molecular mechanisms of epithelial-mesenchymal transition Angiotensin II contributes to renal fibrosis independently of Notch pathway activation Impaired integrin β3 delays endothelial cell regeneration and contributes to arteriovenous graft failure in mice.Complexities of TGF-β targeted cancer therapy.TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression Cellular Plasticity in Prostate Cancer Bone Metastasis Mechanisms of action of TGF-beta in cancer: evidence for Smad3 as a repressor of the hTERT gene Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer Dedifferentiation of foetal CNS stem cells to mesendoderm-like cells through an EMT process The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer TGF-beta-induced epithelial to mesenchymal transition Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation Mechanistic exploration of phthalimide neovascular factor 1 using network analysis tools.Preventive effect of Notch signaling inhibition by a gamma-secretase inhibitor on peritoneal dialysis fluid-induced peritoneal fibrosis in rats Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.Epithelial mesenchymal-like transition occurs in a subset of cells in castration resistant prostate cancer bone metastases.ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression Decreased levels of active SMAD2 correlate with poor prognosis in gastric cancer.BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9

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Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

http://www.wikidata.org/entity/Q37258903

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article científic

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article scientifique

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articolo scientifico

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bilimsel makale

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scientific article published on 19 February 2004

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Integration of TGF-beta/Smad a ...... lial-to-mesenchymal transition

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Integration of TGF-beta/Smad a ...... ial-to-mesenchymal transition.

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Integration of TGF-beta/Smad a ...... lial-to-mesenchymal transition

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Integration of TGF-beta/Smad a ...... ial-to-mesenchymal transition.

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Integration of TGF-beta/Smad a ...... lial-to-mesenchymal transition

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Integration of TGF-beta/Smad a ...... ial-to-mesenchymal transition.

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SJ.EMBOJ.7600069

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The EMBO Journal

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Integration of TGF-beta/Smad a ...... lial-to-mesenchymal transition

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Erwin P Böttinger

http://www.w3.org/2001/XMLSchema#string

Jiri Zavadil

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Lukas Cermak

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Noemi Soto-Nieves

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P2860

Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes

Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling

Epithelial-mesenchymal transitions in tumour progression

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

Notch signaling: from the outside in

The snail superfamily of zinc-finger transcription factors

Smads: transcriptional activators of TGF-beta responses

TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes

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1155-1165

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scholarly article

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10.1038/SJ.EMBOJ.7600069

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5

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23

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2004-02-19T00:00:00Z

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