DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding
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Zelda binding in the early Drosophila melanogaster embryo marks regions subsequently activated at the maternal-to-zygotic transitionConserved nucleosome positioning defines replication originsMechanisms for initiating cellular DNA replicationPeaks cloaked in the mist: the landscape of mammalian replication originsStructural analysis of human Orc6 protein reveals a homology with transcription factor TFIIBHow MCM loading and spreading specify eukaryotic DNA replication initiation sitesHelicase loading at chromosomal origins of replicationBinding of AlF-C, an Orc1-binding transcriptional regulator, enhances replicator activity of the rat aldolase B originTranscription initiation activity sets replication origin efficiency in mammalian cellsHuman origin recognition complex binds preferentially to G-quadruplex-preferable RNA and single-stranded DNAHomeotic proteins participate in the function of human-DNA replication origins.Cooperative DnaA Binding to the Negatively Supercoiled datA Locus Stimulates DnaA-ATP Hydrolysis.De novo assembly of genuine replication forks on an immobilized circular plasmid in Xenopus egg extracts.Atomic force microscopic analysis of the binding of the Schizosaccharomyces pombe origin recognition complex and the spOrc4 protein with origin DNA.Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loadingThe DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation.Studies of the properties of human origin recognition complex and its Walker A motif mutants.Looking at plant cell cycle from the chromatin window.The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin.In search of the holy replicatorThe replicon revisited: an old model learns new tricks in metazoan chromosomesEvaluating genome-scale approaches to eukaryotic DNA replication.Chromatin signatures of the Drosophila replication programCdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication.Defining the replication program through the chromatin landscapePre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zoneSV40 DNA replication: from the A gene to a nanomachine.Molecular determinants of origin discrimination by Orc1 initiators in archaea.The BAH domain facilitates the ability of human Orc1 protein to activate replication origins in vivo.Identification of new human origins of DNA replication by an origin-trapping assay.Crystal structure of the eukaryotic origin recognition complex.The hunt for origins of DNA replication in multicellular eukaryotesA robust assay to measure DNA topology-dependent protein binding affinity.Analysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the prereplicative complexCdc6-induced conformational changes in ORC bound to origin DNA revealed by cryo-electron microscopyGenomic specification and epigenetic regulation of eukaryotic DNA replication originsHigh-resolution profiling of Drosophila replication start sites reveals a DNA shape and chromatin signature of metazoan originsSpecific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues.DNA sequence templates adjacent nucleosome and ORC sites at gene amplification origins in Drosophila.Direct single-molecule observations of DNA unwinding by SV40 large tumor antigen under a negative DNA supercoil state.
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DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 February 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding
@en
DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding.
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type
label
DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding
@en
DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding.
@nl
prefLabel
DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding
@en
DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding.
@nl
P2860
P356
P1433
P1476
DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding
@en
P2093
Eileen L Beall
Michael R Botchan
P2860
P304
P356
10.1038/SJ.EMBOJ.7600077
P407
P50
P577
2004-02-05T00:00:00Z