Alterations in size, number, and morphology of gustatory papillae and taste buds in BDNF null mutant mice demonstrate neural dependence of developing taste organs.
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Innovative Dental Stem Cell-Based Research Approaches: The Future of DentistrySox2 is required for development of taste bud sensory cellsBDNF and NT4 play interchangeable roles in gustatory developmentExpanded terminal fields of gustatory nerves accompany embryonic BDNF overexpression in mouse oral epithelia.Chorda tympani nerve transection at different developmental ages produces differential effects on taste bud volume and papillae morphology in the ratTime course of morphological alterations of fungiform papillae and taste buds following chorda tympani transection in neonatal rats.Fungiform taste bud degeneration in C57BL/6J mice following chorda-lingual nerve transectionEpibranchial placode-derived neurons produce BDNF required for early sensory neuron development.BDNF is required for the survival of differentiated geniculate ganglion neurons.Lingual and palatal gustatory afferents each depend on both BDNF and NT-4, but the dependence is greater for lingual than palatal afferentsFactors that regulate embryonic gustatory development.The neurotrophin receptor p75 regulates gustatory axon branching and promotes innervation of the tongue during development.Accelerated turnover of taste bud cells in mice deficient for the cyclin-dependent kinase inhibitor p27Kip1.Single Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo.Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system.Non-specific immunostaining by a rabbit antibody against gustducin α subunit in mouse brainTaste neurons consist of both a large TrkB-receptor-dependent and a small TrkB-receptor-independent subpopulationEpithelial overexpression of BDNF and NT4 produces distinct gustatory axon morphologies that disrupt initial targeting.Developmental time course of peripheral cross-modal sensory interaction of the trigeminal and gustatory systems.Mice lacking the p75 receptor fail to acquire a normal complement of taste buds and geniculate ganglion neurons by adulthoodRole of the ectonucleotidase NTPDase2 in taste bud functionEpithelial-derived brain-derived neurotrophic factor is required for gustatory neuron targeting during a critical developmental periodNeurotrophin-4 regulates the survival of gustatory neurons earlier in development using a different mechanism than brain-derived neurotrophic factorEphrin-B/EphB Signaling Is Required for Normal Innervation of Lingual Gustatory Papillae.Taste Bud-Derived BDNF Is Required to Maintain Normal Amounts of Innervation to Adult Taste Buds.Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system.Microfluidics co-culture systems for studying tooth innervation.Analysis of Developing Tooth Germ Innervation Using Microfluidic Co-culture Devices.
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P2860
Alterations in size, number, and morphology of gustatory papillae and taste buds in BDNF null mutant mice demonstrate neural dependence of developing taste organs.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on June 1999
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Alterations in size, number, a ...... ce of developing taste organs.
@en
Alterations in size, number, a ...... ce of developing taste organs.
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type
label
Alterations in size, number, a ...... ce of developing taste organs.
@en
Alterations in size, number, a ...... ce of developing taste organs.
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prefLabel
Alterations in size, number, a ...... ce of developing taste organs.
@en
Alterations in size, number, a ...... ce of developing taste organs.
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P2093
P2860
P1476
Alterations in size, number, a ...... ce of developing taste organs.
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P2093
C M Mistretta
K A Goosens
L F Reichardt
P2860
P356
10.1002/(SICI)1096-9861(19990621)409:1<13::AID-CNE2>3.3.CO;2-F
P407
P577
1999-06-01T00:00:00Z