Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior
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Acid-sensing ion channels in pain and disease.Structure and activity of the acid-sensing ion channelsIon channels as drug targets in central nervous system disordersTwo aspects of ASIC function: Synaptic plasticity and neuronal injury.Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype.The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis.Physiological and pathological functions of acid-sensing ion channels in the central nervous system.Acid-sensing ion channels: A new target for pain and CNS diseasesExpressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioningASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversionNutritional psychiatry research: an emerging discipline and its intersection with global urbanization, environmental challenges and the evolutionary mismatchLeukocyte Gene Expression in Patients with Medication Refractory Depression before and after Treatment with ECT or Isoflurane Anesthesia: A Pilot Study.Dysregulation of leukocyte gene expression in women with medication-refractory depression versus healthy non-depressed controls.Extracellular chloride modulates the desensitization kinetics of acid-sensing ion channel 1a (ASIC1a)The human ortholog of acid-sensing ion channel gene ASIC1a is associated with panic disorder and amygdala structure and function.Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant.Linking molecules to mood: new insight into the biology of depression.Acid-Sensing Ion Channel 1a in the amygdala is involved in pain and anxiety-related behaviours associated with arthritis.A HCO(3)(-)-dependent mechanism involving soluble adenylyl cyclase for the activation of Ca²⁺ currents in locus coeruleus neurons.Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation.Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal deathGenetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome.Expression and activity of acid-sensing ion channels in the mouse anterior pituitary.Acidosis-Induced Dysfunction of Cortical GABAergic Neurons through Astrocyte-Related Excitotoxicity.Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC).ENaCs and ASICs as therapeutic targets.A potential role for the acid-sensing T cell death associated gene-8 (TDAG8) receptor in depression-like behavior.Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signaling.Tetramethylpyrazine Produces Antidepressant-Like Effects in Mice Through Promotion of BDNF Signaling Pathway.Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus.Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a.Effects of early-life abuse differ across development: infant social behavior deficits are followed by adolescent depressive-like behaviors mediated by the amygdalaAbnormal activity-dependent brain lactate and glutamate+glutamine responses in panic disorder.The basolateral amygdala γ-aminobutyric acidergic system in health and disease.Alteration by p11 of mGluR5 localization regulates depression-like behaviors.Antidepressant-Like Effects of GM1 Ganglioside Involving the BDNF Signaling Cascade in Mice.Differential regulation of locomotor activity to acute and chronic cocaine administration by acid-sensing ion channel 1a and 2 in adult mice.Acid-sensing ion channels are expressed in the ventrolateral medulla and contribute to central chemoreception.Neurocircuitry underlying stress and emotional regulation in animals prenatally exposed to alcohol and subjected to chronic mild stress in adulthood
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Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Acid-sensing ion channel-1a in ...... in depression-related behavior
@en
Acid-sensing ion channel-1a in ...... n depression-related behavior.
@nl
type
label
Acid-sensing ion channel-1a in ...... in depression-related behavior
@en
Acid-sensing ion channel-1a in ...... n depression-related behavior.
@nl
prefLabel
Acid-sensing ion channel-1a in ...... in depression-related behavior
@en
Acid-sensing ion channel-1a in ...... n depression-related behavior.
@nl
P2093
P2860
P50
P1476
Acid-sensing ion channel-1a in ...... in depression-related behavior
@en
P2093
Adam E Ziemann
Alan R Light
Jason E Allen
Jill M Haenfler
Jon D Rainier
Jonathan P Dunning
Margaret P Price
Matthew W Coryell
Melloni N Cook
Mikael Schnizler
P2860
P304
P356
10.1523/JNEUROSCI.0360-09.2009
P407
P577
2009-04-01T00:00:00Z