Aggregation of membrane proteins by cytosolic cross-linkers: theory and simulation of the LAT-Grb2-SOS1 system
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RuleMonkey: software for stochastic simulation of rule-based modelsUltrasensitivity in multisite phosphorylation of membrane-anchored proteinsQuantifying intramolecular binding in multivalent interactions: a structure-based synergistic study on Grb2-Sos1 complexLive-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosisPhosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS.Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor.Modeling multivalent ligand-receptor interactions with steric constraints on configurations of cell-surface receptor aggregates.Hierarchical graphs for rule-based modeling of biochemical systemsBinding and function of phosphotyrosines of the Ephrin A2 (EphA2) receptor using synthetic sterile α motif (SAM) domains.Modeling and simulation of aggregation of membrane protein LAT with molecular variability in the number of binding sites for cytosolic Grb2-SOS1-Grb2.The efficiency of reactant site sampling in network-free simulation of rule-based models for biochemical systems.Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity.Shaping the response: the role of FcεRI and Syk expression levels in mast cell signalingScaffold-mediated nucleation of protein signaling complexes: elementary principles.An Interaction Library for the FcεRI Signaling NetworkGuidelines for visualizing and annotating rule-based modelsSpatio-temporal signaling in mast cells.The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclustersMultipoint binding of the SLP-76 SH2 domain to ADAP is critical for oligomerization of SLP-76 signaling complexes in stimulated T cells.Regulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells.Efficient stochastic simulation of chemical kinetics networks using a weighted ensemble of trajectories.Analyzing the homeostasis of signaling proteins by a combination of Western blot and fluorescence correlation spectroscopy.Absolute Ligand Discrimination by Dimeric Signaling Receptors.Phase separation of signaling molecules promotes T cell receptor signal transduction.Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation.Dynamic Scaling Analysis of Molecular Motion within the LAT:Grb2:SOS Protein Network on Membranes.Automated visualization of rule-based models.Generalizing Gillespie's Direct Method to Enable Network-Free Simulations.
P2860
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P2860
Aggregation of membrane proteins by cytosolic cross-linkers: theory and simulation of the LAT-Grb2-SOS1 system
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Aggregation of membrane protei ...... on of the LAT-Grb2-SOS1 system
@en
Aggregation of membrane protei ...... n of the LAT-Grb2-SOS1 system.
@nl
type
label
Aggregation of membrane protei ...... on of the LAT-Grb2-SOS1 system
@en
Aggregation of membrane protei ...... n of the LAT-Grb2-SOS1 system.
@nl
prefLabel
Aggregation of membrane protei ...... on of the LAT-Grb2-SOS1 system
@en
Aggregation of membrane protei ...... n of the LAT-Grb2-SOS1 system.
@nl
P2093
P2860
P1433
P1476
Aggregation of membrane protei ...... on of the LAT-Grb2-SOS1 system
@en
P2093
Ambarish Nag
Byron Goldstein
Michael I Monine
P2860
P304
P356
10.1016/J.BPJ.2009.01.019
P407
P50
P577
2009-04-01T00:00:00Z