The accelerated simian immunodeficiency virus macaque model of human immunodeficiency virus-associated neurological disease: from mechanism to treatment.
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Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanismProtease resistant protein cellular isoform (PrP(c)) as a biomarker: clues into the pathogenesis of HANDQuantitation of gene expression in formaldehyde-fixed and fluorescence-activated sorted cellsCD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cellsPersistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV modelEndogenous retroviruses and multiple sclerosis-new pieces to the puzzle.Platelet activation and platelet-monocyte aggregate formation contribute to decreased platelet count during acute simian immunodeficiency virus infection in pig-tailed macaquesTGFβ-Mediated Downregulation of Thrombopoietin Is Associated With Platelet Decline in Asymptomatic SIV InfectionCoordinated regulation of SIV replication and immune responses in the CNS.Hippocampal Neuronal Loss in Infant Macaques Orally Infected with Virulent Simian Immunodeficiency Virus (SIV).Loss of corneal sensory nerve fibers in SIV-infected macaques: an alternate approach to investigate HIV-induced PNS damage.Minocycline inhibition of monocyte activation correlates with neuronal protection in SIV neuroAIDSThree-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomographyEmergence of CD4 independence envelopes and astrocyte infection in R5 simian-human immunodeficiency virus model of encephalitis.Elevated brain monoamine oxidase activity in SIV- and HIV-associated neurological disease.PrPC, the cellular isoform of the human prion protein, is a novel biomarker of HIV-associated neurocognitive impairment and mediates neuroinflammationEarly emergence and selection of a SIV-LTR C/EBP site variant in SIV-infected macaques that increases virus infectivityPeripheral blood invariant natural killer T cells of pig-tailed macaquesMitochondrial dysfunction in distal axons contributes to human immunodeficiency virus sensory neuropathyCombination fluconazole/paroxetine treatment is neuroprotective despite ongoing neuroinflammation and viral replication in an SIV model of HIV neurological disease.Neuroinflammation and virus replication in the spinal cord of simian immunodeficiency virus-infected macaques.AIDS and optic neuritis in a rhesus monkey infected with the R5 clade C SHIV-1157ipd3N4Minocycline fails to modulate cerebrospinal fluid HIV infection or immune activation in chronic untreated HIV-1 infection: results of a pilot studyQuinolinic acid/tryptophan ratios predict neurological disease in SIV-infected macaques and remain elevated in the brain under cART.Early minocycline treatment prevents a decrease in striatal dopamine in an SIV model of HIV-associated neurological disease.Of mice and monkeys: can animal models be utilized to study neurological consequences of pediatric HIV-1 infection?A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral LoadsPersistent Peripheral Nervous System Damage in Simian Immunodeficiency Virus-Infected Macaques Receiving Antiretroviral TherapyMice chronically infected with chimeric HIV resist peripheral and brain superinfection: a model of protective immunity to HIV.Genetic knockouts suggest a critical role for HIV co-receptors in models of HIV gp120-induced brain injuryA plasma microRNA signature of acute lentiviral infection: biomarkers of central nervous system disease.RON receptor tyrosine kinase, a negative regulator of inflammation, is decreased during simian immunodeficiency virus-associated central nervous system diseaseMagnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman PrimatesEnhanced human immunodeficiency virus Type 1 expression and neuropathogenesis in knockout mice lacking Type I interferon responses.Distinct Patterns of Tryptophan Maintenance in Tissues during Kynurenine Pathway Activation in Simian Immunodeficiency Virus-Infected Macaques.A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection.Differential type 1 interferon-regulated gene expression in the brain during AIDS: interactions with viral diversity and neurovirulence.Animal models of HIV peripheral neuropathy.TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages.Non-human primate models of SIV infection and CNS neuropathology.
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The accelerated simian immunodeficiency virus macaque model of human immunodeficiency virus-associated neurological disease: from mechanism to treatment.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The accelerated simian immunod ...... : from mechanism to treatment.
@en
The accelerated simian immunod ...... : from mechanism to treatment.
@nl
type
label
The accelerated simian immunod ...... : from mechanism to treatment.
@en
The accelerated simian immunod ...... : from mechanism to treatment.
@nl
prefLabel
The accelerated simian immunod ...... : from mechanism to treatment.
@en
The accelerated simian immunod ...... : from mechanism to treatment.
@nl
P2093
P1476
The accelerated simian immunod ...... : from mechanism to treatment.
@en
P2093
Janice E Clements
Joseph L Mankowski
Lucio Gama
M Christine Zink
P2888
P304
P356
10.1080/13550280802132832
P577
2008-08-01T00:00:00Z
P5875
P6179
1005194071