Inducible expression of cre recombinase in the retinal pigmented epithelium.
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SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epitheliumTargeted deletion of Vegfa in adult mice induces vision lossEarly AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7Apolipoprotein B-containing lipoproteins in retinal aging and age-related macular degeneration.Age- and gene-dosage-dependent cre-induced abnormalities in the retinal pigment epitheliumMitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degenerationMüller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakageX-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epithelium.Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.Generation of Cre transgenic mice with postnatal RPE-specific ocular expressionAging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins.One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT).Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse.Leukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium.Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice.Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented EpitheliumConditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesisRegulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision.Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1.Retinal pigment epithelial cell necroptosis in response to sodium iodateRas pathway inhibition prevents neovascularization by repressing endothelial cell sprouting.Mislocalisation of BEST1 in iPSC-derived retinal pigment epithelial cells from a family with autosomal dominant vitreoretinochoroidopathy (ADVIRC)A tetracycline-inducible and skeletal muscle-specific Cre recombinase transgenic mouse.Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD.Conditional gene targeting: dissecting the cellular mechanisms of retinal degenerations.Role of tyrosine-sulfated proteins in retinal structure and functionEfficient induction of productive Cre-mediated recombination in retinal pigment epithelium.Repurposing an orally available drug for the treatment of geographic atrophy.Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stressQuantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines.Significance of outer blood-retina barrier breakdown in diabetes and ischemia.Expression of Cre recombinase in retinal Müller cells.Temporal requirement of RPE-derived VEGF in the development of choroidal vasculature.RPE barrier breakdown in diabetic retinopathy: seeing is believing.Metabolic syndrome in mice induced by expressing a transcriptional activator in adipose tissue.Müller cell-derived VEGF is a significant contributor to retinal neovascularization.Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice.Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells.
P2860
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P2860
Inducible expression of cre recombinase in the retinal pigmented epithelium.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inducible expression of cre recombinase in the retinal pigmented epithelium.
@en
Inducible expression of cre recombinase in the retinal pigmented epithelium.
@nl
type
label
Inducible expression of cre recombinase in the retinal pigmented epithelium.
@en
Inducible expression of cre recombinase in the retinal pigmented epithelium.
@nl
prefLabel
Inducible expression of cre recombinase in the retinal pigmented epithelium.
@en
Inducible expression of cre recombinase in the retinal pigmented epithelium.
@nl
P2093
P2860
P356
P1476
Inducible expression of cre recombinase in the retinal pigmented epithelium
@en
P2093
Lixing Zheng
Noriko Esumi
Peng-Cheng Rao
Robert E Anderson
Yun-Zheng Le
P2860
P304
P356
10.1167/IOVS.07-1105
P407
P50
P577
2008-03-01T00:00:00Z