Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles
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Driving with no brakes: molecular pathophysiology of Kv7 potassium channelsApplication of a combination of a knowledge-based algorithm and 2-stage screening to hypothesis-free genomic data on irinotecan-treated patients for identification of a candidate single nucleotide polymorphism related to an adverse effectPeripheral KV7 channels regulate visceral sensory function in mouse and human colon.Differential activation of vascular smooth muscle Kv7.4, Kv7.5, and Kv7.4/7.5 channels by ML213 and ICA-069673.Kv7 and Kv11 channels in myometrial regulation.Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370Expression and function of the K+ channel KCNQ genes in human arteries.Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone.Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretionMolecular expression and pharmacological evidence for a functional role of kv7 channel subtypes in Guinea pig urinary bladder smooth muscleKV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus.Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy.The Novel KV7.2/KV7.3 Channel Opener ICA-069673 Reveals Subtype-Specific Functional Roles in Guinea Pig Detrusor Smooth Muscle Excitability and ContractilityClinical utility, safety, and tolerability of ezogabine (retigabine) in the treatment of epilepsy.One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders.Kv7.5 Potassium Channel Subunits Are the Primary Targets for PKA-Dependent Enhancement of Vascular Smooth Muscle Kv7 Currents.KV7 channels contribute to paracrine, but not metabolic or ischemic, regulation of coronary vascular reactivity in swineFunctional expression of KCNQ (Kv7) channels in guinea pig bladder smooth muscle and their contribution to spontaneous activity.Functional effects of KCNQ K(+) channels in airway smooth muscleDifferential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels.Ionic conductances regulating the excitability of colonic smooth muscles.Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter.Downregulation of KCNQ4 by Janus kinase 2.KV7 Channel Pharmacological Activation by the Novel Activator ML213: Role for Heteromeric KV7.4/KV7.5 Channels in Guinea Pig Detrusor Smooth Muscle Function.TREK-1 Channel Expression in Smooth Muscle as a Target for Regulating Murine Intestinal Contractility: Therapeutic Implications for Motility Disorders.Cholinergic signalling-regulated KV7.5 currents are expressed in colonic ICC-IM but not ICC-MP.Clofibrate relaxes the longitudinal smooth muscle of the mouse distal colon through calcium-mediated desensitisation of contractile machinery.
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Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 23 April 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Molecular and functional chara ...... astrointestinal smooth muscles
@en
Molecular and functional chara ...... strointestinal smooth muscles.
@nl
type
label
Molecular and functional chara ...... astrointestinal smooth muscles
@en
Molecular and functional chara ...... strointestinal smooth muscles.
@nl
prefLabel
Molecular and functional chara ...... astrointestinal smooth muscles
@en
Molecular and functional chara ...... strointestinal smooth muscles.
@nl
P2093
P2860
P356
P1476
Molecular and functional chara ...... astrointestinal smooth muscles
@en
P2093
Iain A Greenwood
James D Moffatt
Susumu Ohya
Thomas A Jepps
P2860
P304
P356
10.1152/AJPGI.00057.2009
P577
2009-04-23T00:00:00Z