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A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes

http://www.wikidata.org/entity/Q37267841

about

Dendritic cell subsets in type 1 diabetes: friend or foe?Micro and nanoparticle drug delivery systems for preventing allotransplant rejection An update on the use of NOD mice to study autoimmune (Type 1) diabetes.Modern Medicine: Towards Prevention, Cure, Well-being and Longevity.Genetic vaccination for re-establishing T-cell tolerance in type 1 diabetes.Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same?A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice.A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice.Microparticle surface modifications targeting dendritic cells for non-activating applications.Development of standardized insulin treatment protocols for spontaneous rodent models of type 1 diabetes.Materials that harness and modulate the immune system.In vivo delivery of nucleic acid-formulated microparticles as a potential tolerogenic vaccine for type 1 diabetes.Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.Inducing immune tolerance: a focus on Type 1 diabetes mellitus.It's time to bring dendritic cell therapy to type 1 diabetes.Impact of T-cell-specific Smad4 deficiency on the development of autoimmune diabetes in NOD mice.Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres Dendritic cell-based therapy in Type 1 diabetes mellitus.The immunotherapeutic potential of dendritic cells in type 1 diabetes.Drug delivery technologies for autoimmune disease.Multifunctional dendritic cell-targeting polymeric microparticles: engineering new vaccines for type 1 diabetes.Tolerance strategies employing antigen-coupled apoptotic cells and carboxylated PLG nanoparticles for the treatment of type 1 diabetes.Strategies to direct the enrichment, expansion, and recruitment of regulatory cells for the treatment of disease.Delivery of siRNAs to Dendritic Cells Using DEC205-Targeted Lipid Nanoparticles to Inhibit Immune Responses.Tolerogenic Nanoparticles to Treat Islet Autoimmunity.Combinatorial drug delivery approaches for immunomodulation.Delivery of rapamycin to dendritic cells using degradable microparticles.An antigen-specific semi-therapeutic treatment with local delivery of tolerogenic factors through a dual-sized microparticle system blocks experimental autoimmune encephalomyelitis.Modulating the immune system through nanotechnology.Therapies to Suppress β Cell Autoimmunity in Type 1 Diabetes

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P2860

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes

http://www.wikidata.org/entity/Q37267841

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 03 March 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes

@en

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes.

@nl

type

label

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes

@en

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes.

@nl

prefLabel

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes

@en

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes.

@nl

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A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes

@en

P2093

Alexis Styche

http://www.w3.org/2001/XMLSchema#string

Brett Phillips

http://www.w3.org/2001/XMLSchema#string

Debra Lafreniere

http://www.w3.org/2001/XMLSchema#string

Janet Knox

http://www.w3.org/2001/XMLSchema#string

Jennifer Machen

http://www.w3.org/2001/XMLSchema#string

Jo Harnaha

http://www.w3.org/2001/XMLSchema#string

Karen Nylander

http://www.w3.org/2001/XMLSchema#string

Kenneth Hogeland

http://www.w3.org/2001/XMLSchema#string

Kimberly Gillis

http://www.w3.org/2001/XMLSchema#string

Larry Brown

http://www.w3.org/2001/XMLSchema#string

P2860

The induction of tolerance by dendritic cells that have captured apoptotic cells

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

Tolerogenic dendritic cells

Molecular aspects of microparticle phagocytosis by dendritic cells.

Type 1 diabetes: new perspectives on disease pathogenesis and treatment.

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes.

Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction.

Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs

Beta cell rest and recovery--does it bring patients with latent autoimmune diabetes in adults to euglycemia?

Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas.

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1544-1555

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scholarly article

P356

10.2337/DB07-0507

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

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57

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2008-03-03T00:00:00Z

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5536604

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18316361

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2713034

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