Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy
about
Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage.Chagas disease research and development: Is there light at the end of the tunnel?Putting Infection Dynamics at the Heart of Chagas Disease.Biological factors that impinge on Chagas disease drug development.The diversity of the Chagas parasite, Trypanosoma cruzi, infecting the main Central American vector, Triatoma dimidiata, from Mexico to Colombia.Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole.Vaccine-linked chemotherapy improves benznidazole efficacy for acute Chagas disease.4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection.Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping.A novel nanoluciferase-based system to monitor Trypanosoma cruzi infection in mice by bioluminescence imaging.Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome.Evolutionary ecology of Chagas disease; what do we know and what do we need?Imaging the development of chronic Chagas disease after oral transmissionAssessing the Effectiveness of Curative Benznidazole Treatment in Preventing Chronic Cardiac Pathology in Experimental Models of Chagas Disease
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P2860
Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 26 February 2016
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Host and parasite genetics sha ...... ics and chronic cardiomyopathy
@en
Host and parasite genetics sha ...... cs and chronic cardiomyopathy.
@nl
type
label
Host and parasite genetics sha ...... ics and chronic cardiomyopathy
@en
Host and parasite genetics sha ...... cs and chronic cardiomyopathy.
@nl
prefLabel
Host and parasite genetics sha ...... ics and chronic cardiomyopathy
@en
Host and parasite genetics sha ...... cs and chronic cardiomyopathy.
@nl
P2093
P2860
P356
P1476
Host and parasite genetics sha ...... ics and chronic cardiomyopathy
@en
P2093
Amanda Fortes Francisco
John M Kelly
Shiromani Jayawardhana
P2860
P304
P356
10.1111/CMI.12584
P577
2016-02-26T00:00:00Z