Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses. - Wikidata - wikimedia - TriplyDB

Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses.

Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses.

http://www.wikidata.org/entity/Q37274424

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Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis Mnk kinase pathway: Cellular functions and biological outcomes Tumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8+ T Cell Responses and Protects against Influenza Virus G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA.Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma.Classical immunomodulatory therapy in multiple sclerosis: how it acts, how it works.Regulatory effects of SKAR in interferon α signaling and its role in the generation of type I IFN responses.Role of interferon {alpha} (IFN{alpha})-inducible Schlafen-5 in regulation of anchorage-independent growth and invasion of malignant melanoma cells.Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor Dual mTORC2/mTORC1 targeting results in potent suppressive effects on acute myeloid leukemia (AML) progenitors.Protein kinase R as mediator of the effects of interferon (IFN) gamma and tumor necrosis factor (TNF) alpha on normal and dysplastic hematopoiesis Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes Interferon-alpha competing endogenous RNA network antagonizes microRNA-1270.Central role of ULK1 in type I interferon signaling Protein kinase PKR catalytic activity is required for the PKR-dependent activation of mitogen-activated protein kinases and amplification of interferon beta induction following virus infection.Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses BANK1 Regulates IgG Production in a Lupus Model by Controlling TLR7-Dependent STAT1 Activation.Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors.The oncogene eIF4E: using biochemical insights to target cancer.Beyond autophagy: New roles for ULK1 in immune signaling and interferon responses.Essential role for the Mnk pathway in the inhibitory effects of type I interferons on myeloproliferative neoplasm (MPN) precursors Translational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs.Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1.Critical roles for Rictor/Sin1 complexes in interferon-dependent gene transcription and generation of antiproliferative responses.The schlafen family of proteins and their regulation by interferons.Multifarious determinants of cytokine receptor signaling specificity.Regulation of interferon-dependent mRNA translation of target genes Interferon receptor signaling in malignancy: a network of cellular pathways defining biological outcomes.The interferon-alpha revival in CML.Differential Regulation of ZEB1 and EMT by MAPK-Interacting Protein Kinases (MNK) and eIF4E in Pancreatic Cancer.Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses.Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells.Interferon-alpha modulates the chemosensitivity of CD133-expressing pancreatic cancer cells to gemcitabine.Type I Interferon-Mediated Induction of Antiviral Genes and Proteins Fails to Protect Cells from the Cytopathic Effects of Sendai Virus Infection.Regulatory effects of programmed cell death 4 (PDCD4) protein in interferon (IFN)-stimulated gene expression and generation of type I IFN responses.Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors.

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Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses.

http://www.wikidata.org/entity/Q37274424

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 02 July 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Type I interferon (IFN)-depend ...... f growth inhibitory responses.

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Type I interferon

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type

label

Type I interferon (IFN)-depend ...... f growth inhibitory responses.

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Type I interferon

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prefLabel

Type I interferon (IFN)-depend ...... f growth inhibitory responses.

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Type I interferon

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PNAS.0900562106

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Proceedings of the National Academy of Sciences of the United States of America

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Type I interferon (IFN)-depend ...... f growth inhibitory responses.

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Amanda J Redig

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Darren P Baker

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Katy Goldsborough

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Kevin David

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Leonidas C Platanias

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Rie Watanabe-Fukunaga

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Rikiro Fukunaga

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Sonali Joshi

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Surinder Kaur

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Takeshi Ueda

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Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

Suppression of cap-dependent translation in mitosis

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

How cells respond to interferons

Mechanisms of type-I- and type-II-interferon-mediated signalling

Interferon-gamma engages the p70 S6 kinase to regulate phosphorylation of the 40S S6 ribosomal protein

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12097-12102

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scholarly article

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10.1073/PNAS.0900562106

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29

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106

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Eleanor N. Fish

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2009-07-02T00:00:00Z

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26337966

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19574459

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2715502

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