Synergism between arsenic trioxide and heat shock protein 90 inhibitors on signal transducer and activator of transcription protein 3 activity--pharmacodynamic drug-drug interaction modeling
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Geldanamycin induces production of heat shock protein 70 and partially attenuates ototoxicity caused by gentamicin in the organ of Corti explantsHsp70 and its molecular role in nervous system diseasesPhase 1 study of arsenic trioxide, high-dose cytarabine, and idarubicin to down-regulate constitutive signal transducer and activator of transcription 3 activity in patients aged <60 years with acute myeloid leukemiaDown-regulation of heat shock protein 70 improves arsenic trioxide and 17-DMAG effects on constitutive signal transducer and activator of transcription 3 activityInhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline.Synergism between clofarabine and decitabine through p53R2: a pharmacodynamic drug-drug interaction modeling.Targeting signal transducer and activator of transcription signaling pathway in leukemias.Biological responses to arsenic compoundsInhibition of the heat shock response by PI103 enhances the cytotoxicity of arsenic trioxide.Assessment of non-linear combination effect terms for drug-drug interactions.Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90).
P2860
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P2860
Synergism between arsenic trioxide and heat shock protein 90 inhibitors on signal transducer and activator of transcription protein 3 activity--pharmacodynamic drug-drug interaction modeling
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Synergism between arsenic trio ...... drug-drug interaction modeling
@en
Synergism between arsenic trio ...... rug-drug interaction modeling.
@nl
type
label
Synergism between arsenic trio ...... drug-drug interaction modeling
@en
Synergism between arsenic trio ...... rug-drug interaction modeling.
@nl
prefLabel
Synergism between arsenic trio ...... drug-drug interaction modeling
@en
Synergism between arsenic trio ...... rug-drug interaction modeling.
@nl
P2093
P2860
P1476
Synergism between arsenic trio ...... drug-drug interaction modeling
@en
P2093
Justin C Earp
Meir Wetzler
Michael K Keng
Michael T Brady
William J Jusko
P2860
P304
P356
10.1158/1078-0432.CCR-06-2468
P407
P577
2007-04-01T00:00:00Z