Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells

Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells

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http://www.wikidata.org/entity/Q37276844
Preclinical evidences toward the use of triterpenoid CDDO-Me for solid cancer prevention and treatmentProteomic analysis shows synthetic oleanane triterpenoid binds to mTORBardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties.Cellular stress-induced up-regulation of FMRP promotes cell survival by modulating PI3K-Akt phosphorylation cascadesPrevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate CancerSynthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease.Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses.The triterpenoid CDDO-Me promotes hematopoietic progenitor expansion and myelopoiesis in mice.Bardoxolone Methyl Prevents High-Fat Diet-Induced Colon Inflammation in Mice.Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.Targeting nrf2-mediated gene transcription by triterpenoids and their derivatives.The Synthetic Triterpenoid RTA 405 (CDDO-EA) Halts Progression of Liver Fibrosis and Reduces Hepatocellular Carcinoma Size Resulting in Increased Survival in an Experimental Model of Chronic Liver Injury.
P2860

Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells

Item
http://www.wikidata.org/entity/Q37276844
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Synthetic triterpenoids inhibi ...... ins in colorectal cancer cells
@en
Synthetic triterpenoids inhibi ...... ns in colorectal cancer cells.
@nl
type
label
Synthetic triterpenoids inhibi ...... ins in colorectal cancer cells
@en
Synthetic triterpenoids inhibi ...... ns in colorectal cancer cells.
@nl
prefLabel
Synthetic triterpenoids inhibi ...... ins in colorectal cancer cells
@en
Synthetic triterpenoids inhibi ...... ns in colorectal cancer cells.
@nl
P1433
P1476
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P921
P932
P1433
P1476
Synthetic triterpenoids inhibi ...... ins in colorectal cancer cells
@en
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P921
P932