Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
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Regulation of glucose and glycogen metabolism during and after exerciseThe Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular DiseaseCounteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein PhosphatasesCardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failureA compartmentalized mathematical model of the β1-adrenergic signaling system in mouse ventricular myocytesCaMKII-dependent responses to ischemia and reperfusion challenges in the heart.Phosphoprotein abundance changes in hypertensive cardiac remodeling.Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways.Signaling and myosin-binding protein C.Redox signaling and cardiac sarcomeresThe large isoforms of A-kinase anchoring protein 18 mediate the phosphorylation of inhibitor-1 by protein kinase A and the inhibition of protein phosphatase 1 activity.p38α regulates SERCA2a function.Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts.ERK/PP1a/PLB/SERCA2a and JNK pathways are involved in luteolin-mediated protection of rat hearts and cardiomyocytes following ischemia/reperfusion.AKAPs: the architectural underpinnings of local cAMP signaling.A Decoy Peptide Targeted to Protein Phosphatase 1 Attenuates Degradation of SERCA2a in Vascular Smooth Muscle Cells.Abnormalities of calcium handling proteins in skeletal muscle mirror those of the heart in humans with heart failure: a shared mechanism?Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterationsCardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulationHuman G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias.Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging.Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman.β-adrenergic stimulation activates early afterdepolarizations transiently via kinetic mismatch of PKA targets.Altered sarcoplasmic reticulum calcium cycling--targets for heart failure therapy.Cardiomyocyte specific deletion of PP2A causes cardiac hypertrophy.Contractile protein phosphorylation predicts human heart disease phenotypesImpaired assembly and post-translational regulation of 26S proteasome in human end-stage heart failure.Sarcoplasmic reticulum Ca2+ cycling protein phosphorylation in a physiologic Ca2+ milieu unleashes a high-power, rhythmic Ca2+ clock in ventricular myocytes: relevance to arrhythmias and bio-pacemaker design.Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure.AKAP phosphatase complexes in the heart.Targeted gene therapy for the treatment of heart failure.Calcium cycling proteins and their association with heart failure.Cardiac gene therapy: from concept to reality.Phospholamban and cardiac function: a comparative perspective in vertebrates.I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model.Phospholamban and sarcolipin: Are they functionally redundant or distinct regulators of the Sarco(Endo)Plasmic Reticulum Calcium ATPase?Regulation of sarcoplasmic reticulum Ca2+ release by serine-threonine phosphatases in the heart.Calcineurin signaling in the heart: The importance of time and place.Phospholamban mutants compete with wild type for SERCA binding in living cells.Miklós Bodanszky Award Lecture: Advances in the selective targeting of protein phosphatase-1 and phosphatase-2A with peptides.
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Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 27 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
@en
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
@nl
type
label
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
@en
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
@nl
prefLabel
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
@en
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
@nl
P2093
P2860
P1476
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
@en
P2093
Evangelia G Kranias
Persoulla Nicolaou
Roger J Hajjar
P2860
P304
P356
10.1016/J.YJMCC.2009.05.010
P577
2009-05-27T00:00:00Z