Functional enhancers at the gene-poor 8q24 cancer-linked locus.
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A user's guide to the encyclopedia of DNA elements (ENCODE)Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseasesMultiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loopsHERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoterGenomics era and complex disorders: Implications of GWAS with special reference to coronary artery disease, type 2 diabetes mellitus, and cancersRegulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancerThe complexity of epigenetic diseasesEnhancer malfunction in cancerThe genetics of cancer riskThe emergence of lncRNAs in cancer biologyMale pattern baldness in relation to prostate cancer risks: an analysis in the VITamins and lifestyle (VITAL) cohort study.The Archon Genomics X PRIZE for whole human genome sequencingA genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.Discovery and characterization of chromatin states for systematic annotation of the human genomeA genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2Genome-wide epigenetic data facilitate understanding of disease susceptibility association studies.FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding protein 3 pathway.Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells.Estimation and partition of heritability in human populations using whole-genome analysis methods.Modulation of androgen receptor by FOXA1 and FOXO1 factors in prostate cancer.Characterizing genetic risk at known prostate cancer susceptibility loci in African AmericansNOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations.Prostate cancer risk alleles are associated with prostate cancer volume and prostate size.Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits.A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression.Association between genetic variants in the 8q24 cancer risk regions and circulating levels of androgens and sex hormone-binding globulin.8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.Genetic variation at chromosome 8q24 in osteosarcoma cases and controls.An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer.Molecular genetics of prostate cancer: new prospects for old challengesPositive regulation of c-Myc by cohesin is direct, and evolutionarily conserved.Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancerFunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPsA NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancerGenomics meets proteomics: identifying the culprits in disease.Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA formsAssociations between gene expression variations and ovarian cancer risk alleles identified from genome wide association studiesCohesin is required for activation of MYC by estradiol.A genome-wide scan for breast cancer risk haplotypes among African American women
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Functional enhancers at the gene-poor 8q24 cancer-linked locus.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 14 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
@en
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
@nl
type
label
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
@en
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
@nl
prefLabel
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
@en
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
@nl
P2093
P2860
P50
P1433
P1476
Functional enhancers at the gene-poor 8q24 cancer-linked locus
@en
P2093
Amos Tanay
Baruch Frenkel
Brian E Henderson
Christopher A Haiman
Chunli Yan
David Reich
Gerhard A Coetzee
Gilad Landan
Mark Pomerantz
P2860
P304
P356
10.1371/JOURNAL.PGEN.1000597
P577
2009-08-14T00:00:00Z