Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation.
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High levels of anti-inflammatory and pro-resolving lipid mediators lipoxins and resolvins and declining docosahexaenoic acid levels in human milk during the first month of lactationMouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptorRecent progress on acyl CoA: lysophospholipid acyltransferase researchResolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancerMetabolic functions of FABPs--mechanisms and therapeutic implicationsSphingolipid signaling in metabolic disordersLipid mediators and allergic diseasesThe E2F2 transcription factor sustains hepatic glycerophospholipid homeostasis in miceLysophospholipid receptors in drug discovery.The platelet activating factor (PAF) signaling cascade in systemic inflammatory responsesIdentification of resolvin D2 receptor mediating resolution of infections and organ protectionResolvin D1 binds human phagocytes with evidence for proresolving receptorsProtectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolomeRole of platelets in neuroinflammation: a wide-angle perspectiveStatistical analysis of the processes controlling choline and ethanolamine glycerophospholipid molecular species compositionMast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axisEmerging targets in lipid-based therapyPGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lungResolvin E1 receptor activation signals phosphorylation and phagocytosis.Targeted quantitative analysis of eicosanoid lipids in biological samples using liquid chromatography-tandem mass spectrometry.Targeted chiral lipidomics analysis of bioactive eicosanoid lipids in cellular systems.Working towards an exegesis for lipids in biology.Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsisFracture healing and lipid mediators.Novel lipid mediators and resolution mechanisms in acute inflammation: to resolve or not?Lipid signaling in cytosolic phospholipase A2alpha-cyclooxygenase-2 cascade mediates cerebellar long-term depression and motor learning.Relief from neuropathic pain by blocking of the platelet-activating factor-pain loopIn search of analgesia: emerging roles of GPCRs in pain.Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue.Carboxylesterases: Dual roles in lipid and pesticide metabolism.A mathematical model for the determination of steady-state cardiolipin remodeling mechanisms using lipidomic data.The endocannabinoid system: potential for reducing cardiometabolic riskUnraveling the complex relationship triad between lipids, obesity, and inflammationRapid production of platelet-activating factor is induced by protein kinase Cα-mediated phosphorylation of lysophosphatidylcholine acyltransferase 2 proteinPlatelet-activating factor receptor agonists mediate xeroderma pigmentosum A photosensitivity.Prostaglandins and inflammation.Resolvin E1 regulates adenosine diphosphate activation of human platelets.Novel n-3 immunoresolvents: structures and actions
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Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Lipid mediators in health and ...... of immunity and inflammation.
@en
Lipid mediators in health and ...... of immunity and inflammation.
@nl
type
label
Lipid mediators in health and ...... of immunity and inflammation.
@en
Lipid mediators in health and ...... of immunity and inflammation.
@nl
prefLabel
Lipid mediators in health and ...... of immunity and inflammation.
@en
Lipid mediators in health and ...... of immunity and inflammation.
@nl
P1476
Lipid mediators in health and ...... of immunity and inflammation.
@en
P2093
Takao Shimizu
P304
P356
10.1146/ANNUREV.PHARMTOX.011008.145616
P577
2009-01-01T00:00:00Z