The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression
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The role of cullin 5-containing ubiquitin ligasesSOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokinesThe biology and mechanism of action of suppressor of cytokine signaling 3Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin LigaseSOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibitionMultimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin LigasesStructural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexesThe SOCS2 ubiquitin ligase complex regulates growth hormone receptor levelsMolecular insight into the conformational dynamics of the Elongin BC complex and its interaction with HIV-1 Vif.HTLV-1 evades type I interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1)Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates.Extended anti-inflammatory action of a degradation-resistant mutant of cell-penetrating suppressor of cytokine signaling 3.Core-binding factor β increases the affinity between human Cullin 5 and HIV-1 Vif within an E3 ligase complexThe role of the cullin-5 e3 ubiquitin ligase in the regulation of insulin receptor substrate-1.New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries.The kinase inhibitory region of SOCS-1 is sufficient to inhibit T-helper 17 and other immune functions in experimental allergic encephalomyelitisBiophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complexSuppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases.Janus kinase 3: the controller and the controlledSuppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity.The Role of Elongin BC-Containing Ubiquitin Ligases.miR-9 Acts as an OncomiR in Prostate Cancer through Multiple Pathways That Drive Tumour Progression and Metastasis.Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins.Biology and significance of the JAK/STAT signalling pathways.Socs36E attenuates STAT signaling to optimize motile cell specification in the Drosophila ovaryDrosophila SOCS36E negatively regulates JAK/STAT pathway signaling via two separable mechanisms.Regulation of Janus kinases by SOCS proteins.Suppression of cytokine signaling: the SOCS perspective.BC-box protein domain-related mechanism for VHL protein degradation.SOCS3, a Major Regulator of Infection and Inflammation.Erythropoietin receptor response circuitsRegulation of CD4+ T-cell polarization by suppressor of cytokine signalling proteins.The SOCS box-adapting proteins for ubiquitination and proteasomal degradation.Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity.SOCS proteins in development and disease.Regulation of neurotrophin receptor (Trk) signaling: suppressor of cytokine signaling 2 (SOCS2) is a new player.Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression.Cell regulation by phosphotyrosine-targeted ubiquitin ligases.
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The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on March 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The SOCS box encodes a hierarc ...... ytokine signalling suppression
@en
The SOCS box encodes a hierarc ...... tokine signalling suppression.
@nl
type
label
The SOCS box encodes a hierarc ...... ytokine signalling suppression
@en
The SOCS box encodes a hierarc ...... tokine signalling suppression.
@nl
prefLabel
The SOCS box encodes a hierarc ...... ytokine signalling suppression
@en
The SOCS box encodes a hierarc ...... tokine signalling suppression.
@nl
P2093
P2860
P1476
The SOCS box encodes a hierarc ...... ytokine signalling suppression
@en
P2093
Jennifer K Sabo
Jian-Guo Zhang
Raymond S Norton
P2860
P304
P356
10.1016/J.JMB.2009.01.024
P407
P577
2009-03-01T00:00:00Z