The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and drug transport by Pim-1-dependent and -independent mechanisms

The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and drug transport by Pim-1-dependent and -independent mechanisms

Item
http://www.wikidata.org/entity/Q37289700
Targeting the Pim kinases in multiple myelomaTargeting Pim kinases for cancer treatment: opportunities and challengesPim-1 kinase as cancer drug target: An updatePim-1 acts as an oncogene in human salivary gland adenoid cystic carcinomaA 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function.Human ABCB1 (P-glycoprotein) and ABCG2 mediate resistance to BI 2536, a potent and selective inhibitor of Polo-like kinase 1PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value.PIM kinases: an overview in tumors and recent advances in pancreatic cancer.Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivoOvercoming ABCG2-mediated drug resistance with imidazo-[1,2-b]-pyridazine-based Pim1 kinase inhibitors.Pim kinase isoforms: devils defending cancer cells from therapeutic and immune attacks.ABCG2/BCRP: Specific and Nonspecific Modulators.PIM-1 mRNA expression is a potential prognostic biomarker in acute myeloid leukemia.Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia.Tyrphostin RG14620 selectively reverses ABCG2-mediated multidrug resistance in cancer cell lines.The positive inotropic agent DPI-201106 selectively reverses ABCB1-mediated multidrug resistance in cancer cell lines
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The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and drug transport by Pim-1-dependent and -independent mechanisms

Item
http://www.wikidata.org/entity/Q37289700
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 December 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The Pim kinase inhibitor SGI-1 ...... nt and -independent mechanisms
@en
The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein
@nl
type
label
The Pim kinase inhibitor SGI-1 ...... nt and -independent mechanisms
@en
The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein
@nl
prefLabel
The Pim kinase inhibitor SGI-1 ...... nt and -independent mechanisms
@en
The Pim kinase inhibitor SGI-1776 decreases cell surface expression of P-glycoprotein
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
The Pim kinase inhibitor SGI-1 ...... nt and -independent mechanisms
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932