Nicotine stimulates pancreatic cancer xenografts by systemic increase in stress neurotransmitters and suppression of the inhibitory neurotransmitter gamma-aminobutyric acid.
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Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment - A ReviewThe Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and ProgressionInterplay between smoking-induced genotoxicity and altered signaling in pancreatic carcinogenesisComprehensive review of epidemiological and animal studies on the potential carcinogenic effects of nicotine per sePharmacological Intervention through Dietary Nutraceuticals in Gastrointestinal Neoplasia.Regional metabolite levels and turnover in the awake rat brain under the influence of nicotine.Chronic stress accelerates pancreatic cancer growth and invasion: a critical role for beta-adrenergic signaling in the pancreatic microenvironment.Cooperative regulation of non-small cell lung carcinoma by nicotinic and beta-adrenergic receptors: a novel target for intervention.Effects of tobacco smoking and nicotine on cancer treatment.Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma.Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium.Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed miceNicotinic acetylcholine receptor signaling in tumor growth and metastasisEpigenetic effects and molecular mechanisms of tumorigenesis induced by cigarette smoke: an overviewHarmful effects of nicotine.Differential modulation of nicotine-induced gemcitabine resistance by GABA receptor agonists in pancreatic cancer cell xenografts and in vitroBeta-adrenergic signaling, a novel target for cancer therapy?Regulation of pancreatic cancer by neuropsychological stress responses: a novel target for intervention.Social stress promotes and γ-aminobutyric acid inhibits tumor growth in mouse models of non-small cell lung cancerPancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors α3, α5, and α7.Chronic nicotine consumption does not influence 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesisNicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors.β-blockers: a novel class of antitumor agents.Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters.The pathobiological impact of cigarette smoke on pancreatic cancer development (review).Beta-adrenergic signaling in the development and progression of pulmonary and pancreatic adenocarcinomaNicotine inhibits memory CTL programmingEffects of tobacco constituents and psychological stress on the beta-adrenergic regulation of non-small cell lung cancer and pancreatic cancer: implications for intervention.Prevention of pancreatic cancer in a hamster model by cAMP decrease.Nicotine dependence may link the 15q25 locus to lung cancer risk.Neurotransmitter receptors as central regulators of pancreatic cancerGABA (γ-aminobutyric acid), a non-protein amino acid counters the β-adrenergic cascade-activated oncogenic signaling in pancreatic cancer: a review of experimental evidence.Effects on DNA Damage and/or Repair Processes as Biological Mechanisms Linking Psychological Stress to Cancer RiskNeuroendocrine factors: The missing link in non‑melanoma skin cancer (Review).Nicotine induces self-renewal of pancreatic cancer stem cells via neurotransmitter-driven activation of sonic hedgehog signalling.Nicotinic acetylcholine receptors and cancer.Chronic nicotine inhibits the therapeutic effects of gemcitabine on pancreatic cancer in vitro and in mouse xenografts.New molecular insights in tobacco-induced lung cancer.Role of the nervous system in cancer metastasis.Suppression of Human Liver Cancer Cell Migration and Invasion via the GABAA Receptor.
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P2860
Nicotine stimulates pancreatic cancer xenografts by systemic increase in stress neurotransmitters and suppression of the inhibitory neurotransmitter gamma-aminobutyric acid.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Nicotine stimulates pancreatic ...... itter gamma-aminobutyric acid.
@en
Nicotine stimulates pancreatic ...... itter gamma-aminobutyric acid.
@nl
type
label
Nicotine stimulates pancreatic ...... itter gamma-aminobutyric acid.
@en
Nicotine stimulates pancreatic ...... itter gamma-aminobutyric acid.
@nl
prefLabel
Nicotine stimulates pancreatic ...... itter gamma-aminobutyric acid.
@en
Nicotine stimulates pancreatic ...... itter gamma-aminobutyric acid.
@nl
P2093
P2860
P356
P1433
P1476
Nicotine stimulates pancreatic ...... itter gamma-aminobutyric acid.
@en
P2093
Hildegard M Schuller
Howard K Plummer
Hussein A N Al-Wadei
P2860
P304
P356
10.1093/CARCIN/BGP010
P407
P577
2009-01-08T00:00:00Z