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Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study

Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study

http://www.wikidata.org/entity/Q37294020

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A Cellular GWAS Approach to Define Human Variation in Cellular Pathways Important to Inflammation Redox regulation of mitochondrial biogenesis Sepsis-induced Cardiac Mitochondrial Damage and Potential Therapeutic Interventions in the Elderly PAMPs and DAMPs: signal 0s that spur autophagy and immunity The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti-inflammatory response, and regulatory T cells The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome The intelligence paradox; will ET get the metabolic syndrome? Lessons from and for Earth.Protease 3C of hepatitis A virus induces vacuolization of lysosomal/endosomal organelles and caspase-independent cell death Kinetics and protective role of autophagy in a mouse cecal ligation and puncture-induced sepsis Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock Cell death and inflammatory bowel diseases: apoptosis, necrosis, and autophagy in the intestinal epithelium.Abandon the mouse research ship? Not just yet!Survival in critical illness is associated with early activation of mitochondrial biogenesis.Systems biology of the autophagy-lysosomal pathway.Autophagy-related IRGM polymorphism is associated with mortality of patients with severe sepsis Adenosine monophosphate-activated protein kinase activation protects against sepsis-induced organ injury and inflammation Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy.T-cell autophagy deficiency increases mortality and suppresses immune responses after sepsis.Intestinal epithelium is more susceptible to cytopathic injury and altered permeability than the lung epithelium in the context of acute sepsis.Mitochondrial dysfunction and biogenesis: do ICU patients die from mitochondrial failure?Splenocyte apoptosis and autophagy is mediated by interferon regulatory factor 1 during murine endotoxemia Enhanced liver autophagic activity improves survival of septic mice lacking surfactant proteins A and D.MITOCHONDRIAL FUNCTION IN SEPSIS.Mechanisms of cardiac and renal dysfunction in patients dying of sepsis Experimental sepsis-induced mitochondrial biogenesis is dependent on autophagy, TLR4, and TLR9 signaling in liver.Lipopolysaccharide stimulates p62-dependent autophagy-like aggregate clearance in hepatocytes.Genipin alleviates sepsis-induced liver injury by restoring autophagy Suppression of T Cell Autophagy Results in Decreased Viability and Function of T Cells Through Accelerated Apoptosis in a Murine Sepsis Model.Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes.Pharmacological targets in the renal peritubular microenvironment: implications for therapy for sepsis-induced acute kidney injury.Autophagy and inflammatory diseases.Platelet vacuoles in a dog with severe nonregenerative anemia: evidence of platelet autophagy.Mitochondria-meditated pathways of organ failure upon inflammation.Autophagy in Pulmonary Diseases.Autophagy in inflammatory diseases Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice Association between genetic polymorphisms in the autophagy-related 5 gene promoter and the risk of sepsis.Autophagy confers resistance to lipopolysaccharide-induced mouse hepatocyte injury.Autophagy in sepsis: Degradation into exhaustion?

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Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study

http://www.wikidata.org/entity/Q37294020

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article científic

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bilimsel makale

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scientific article published on 02 February 2009

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Sepsis induces extensive autop ...... cal and laboratory-based study

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Sepsis induces extensive autop ...... al and laboratory-based study.

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Sepsis induces extensive autop ...... cal and laboratory-based study

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LABINVEST.2009.8

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Laboratory Investigation

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Sepsis induces extensive autop ...... cal and laboratory-based study

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Christopher G Davis

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Daniel J Brackett

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David J Dixon

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Eizo Watanabe

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Jared T Muenzer

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Megan R Lerner

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Paul E Swanson

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William G Hawkins

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Gene ontology: tool for the unification of biology

KEGG: kyoto encyclopedia of genes and genomes

Cytoplasmic components in hepatic cell lysosomes

PD-1 and its ligands in tolerance and immunity

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

The role of autophagy during the early neonatal starvation period

Autophagy: from phenomenology to molecular understanding in less than a decade

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labinvest.2009.8

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549-561

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10.1038/LABINVEST.2009.8

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5

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89

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Jonathan E. McDunn

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2009-02-02T00:00:00Z

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19188912

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