Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle
about
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in individual and meta-analysis studies.A New Insight into the Role of Calpains in Post-mortem Meat Tenderization in Domestic Animals: A review.Expression profiling of FSHD-1 and FSHD-2 cells during myogenic differentiation evidences common and distinctive gene dysregulation patternsRedox state and mitochondrial respiratory chain function in skeletal muscle of LGMD2A patients.A transcriptome signature of endothelial lymphatic cells coexists with the chronic oxidative stress signature in radiation-induced post-radiotherapy breast angiosarcomas.The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans.Delineating the role of alterations in lipid metabolism to the pathogenesis of inherited skeletal and cardiac muscle disorders: Thematic Review Series: Genetics of Human Lipid Diseases.A Proof of Concept to Bridge the Gap between Mass Spectrometry Imaging, Protein Identification and Relative Quantitation: MSI~LC-MS/MS-LFImpaired calcium calmodulin kinase signaling and muscle adaptation response in the absence of calpain 3Attenuated Ca(2+) release in a mouse model of limb girdle muscular dystrophy 2A.Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy).Dysregulation of calcium homeostasis in muscular dystrophies.Calpain-14 and its association with eosinophilic esophagitis.Oxidative damage in muscular dystrophy correlates with the severity of the pathology: role of glutathione metabolism.Muscle biopsies from human muscle diseases with myopathic pathology reveal common alterations in mitochondrial function.PLEIAD/SIMC1/C5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpain, CAPN3, scaffolds a CAPN3 substrate, CTBP1.Reduced skeletal muscle fiber size following caloric restriction is associated with calpain-mediated proteolysis and attenuation of IGF-1 signaling.Impaired regeneration in calpain-3 null muscle is associated with perturbations in mTORC1 signaling and defective mitochondrial biogenesis.Oxidative stress, NF-κB and the ubiquitin proteasomal pathway in the pathology of calpainopathy.Calpain 3 and CaMKIIβ signaling are required to induce HSP70 necessary for adaptive muscle growth after atrophy.
P2860
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P2860
Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 29 May 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
@cs
name
Mitochondrial abnormalities, e ...... deficiency in skeletal muscle
@en
Mitochondrial abnormalities, e ...... deficiency in skeletal muscle.
@nl
type
label
Mitochondrial abnormalities, e ...... deficiency in skeletal muscle
@en
Mitochondrial abnormalities, e ...... deficiency in skeletal muscle.
@nl
prefLabel
Mitochondrial abnormalities, e ...... deficiency in skeletal muscle
@en
Mitochondrial abnormalities, e ...... deficiency in skeletal muscle.
@nl
P2093
P2860
P356
P1476
Mitochondrial abnormalities, e ...... deficiency in skeletal muscle
@en
P2093
Irina Kramerova
Krista Vandenborne
M Anthony Verity
Melissa J Spencer
Nadine Romain
Ronald G Haller
Sean Germain
P2860
P304
P356
10.1093/HMG/DDP257
P577
2009-05-29T00:00:00Z