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Sumoylation in Synaptic Function and DysfunctionSUMOylation: Novel Neuroprotective Approach for Alzheimer's Disease?Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulatorsSUMO1 Affects Synaptic Function, Spine Density and MemorySUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3Predicting sumoylation sites using support vector machines based on various sequence features, conformational flexibility and disorder.Protein post-translational modifications: In silico prediction tools and molecular modeling.Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesAβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer's diseaseShp2 SUMOylation promotes ERK activation and hepatocellular carcinoma development.Targeting intrinsically disordered proteins in rational drug discovery.Ginkgolic Acid Protects against Aβ-Induced Synaptic Dysfunction in the Hippocampus.Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease.Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease.Tau-induced neurodegeneration: mechanisms and targets.Overexpression of Ubiquilin-1 Alleviates Alzheimer's Disease-Caused Cognitive and Motor Deficits and Reduces Amyloid-β Accumulation in Mice.A high-yield double-purification proteomics strategy for the identification of SUMO sites.Targeting SUMO-1ylation Contrasts Synaptic Dysfunction in a Mouse Model of Alzheimer's Disease.The Roles of SUMO in Metabolic Regulation.BARHL1 Is Downregulated in Alzheimer's Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways.SUMOylation in brain ischemia: Patterns, targets, and translational implications.SUMO1-conjugation is altered during normal aging but not by increased amyloid burden.SUMOylation in neuroplasticity and neurological disorders.SENP1 and SENP2 regulate SUMOylation of amyloid precursor protein.Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter.Minimotifs dysfunction is pervasive in neurodegenerative disordersSUMOgo: Prediction of sumoylation sites on lysines by motif screening models and the effects of various post-translational modificationsAmyloid assembly and disassembly
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description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 25 August 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
SUMO and Alzheimer's disease.
@en
SUMO and Alzheimer's disease.
@nl
type
label
SUMO and Alzheimer's disease.
@en
SUMO and Alzheimer's disease.
@nl
prefLabel
SUMO and Alzheimer's disease.
@en
SUMO and Alzheimer's disease.
@nl
P2093
P2860
P1476
SUMO and Alzheimer's disease.
@en
P2093
Mikako Sakurai
Paul Fraser
Shinsuke Matsuzaki
P2860
P2888
P304
P356
10.1007/S12017-013-8257-7
P577
2013-08-25T00:00:00Z