siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury - Wikidata - wikimedia - TriplyDB

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

http://www.wikidata.org/entity/Q37297709

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Primary proximal tubule injury leads to epithelial cell cycle arrest, fibrosis, vascular rarefaction, and glomerulosclerosis Remedial applications of silencing ribonucleic acids and modalities for its delivery to the kidneys--a review Mechanisms of Cisplatin nephrotoxicity Fighting against kidney diseases with small interfering RNA: opportunities and challenges Small RNA Detection by in Situ Hybridization Methods An integrated view of cisplatin-induced nephrotoxicity and ototoxicity Cisplatin-induced Kidney Dysfunction and Perspectives on Improving Treatment Strategies Pathogenesis of acute kidney injury: foundation for clinical practice.Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation Therapeutic translation in acute kidney injury: the epithelial/endothelial axis Augmentation of NAD(+) by NQO1 attenuates cisplatin-mediated hearing impairment.MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury.Advances in Systemic siRNA Delivery Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells.DNA damage response in renal ischemia-reperfusion and ATP-depletion injury of renal tubular cells Regulation of necrotic cell death: p53, PARP1 and cyclophilin D-overlapping pathways of regulated necrosis?Suppressed autophagic response underlies augmentation of renal ischemia/reperfusion injury by type 2 diabetes.Pathologies associated with the p53 response.Megalin-mediated specific uptake of chitosan/siRNA nanoparticles in mouse kidney proximal tubule epithelial cells enables AQP1 gene silencing.Multiple analytical approaches demonstrate a complex relationship of genetic and nongenetic factors with cisplatin- and carboplatin-induced nephrotoxicity in lung cancer patients Tubular p53 regulates multiple genes to mediate AKI Analysis of plant-derived miRNAs in animal small RNA datasets Dynamic multiphoton microscopy: focusing light on acute kidney injury.Transcriptome analysis of renal ischemia/reperfusion injury and its modulation by ischemic pre-conditioning or hemin treatment.Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2.Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury A method to facilitate and monitor expression of exogenous genes in the rat kidney using plasmid and viral vectors.Hyperglycemia, p53, and mitochondrial pathway of apoptosis are involved in the susceptibility of diabetic models to ischemic acute kidney injury.Chitosan/siRNA nanoparticles targeting cyclooxygenase type 2 attenuate unilateral ureteral obstruction-induced kidney injury in mice.TIGAR regulates glycolysis in ischemic kidney proximal tubules.Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury.Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer Harnessing RNAi nanomedicine for precision therapy Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane.MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury.Folate receptor-targeted antioxidant therapy ameliorates renal ischemia-reperfusion injury.Alterations in nuclear pore architecture allow cancer cell entry into or exit from drug-resistant dormancy.The first decade of using multiphoton microscopy for high-power kidney imaging.The p53 inhibitor pifithrin-α can stimulate fibrosis in a rat model of ischemic acute kidney injury.

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P2860

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

http://www.wikidata.org/entity/Q37297709

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 21 May 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

@en

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury.

@nl

type

label

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

@en

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury.

@nl

prefLabel

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

@en

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury.

@nl

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Journal of the American Society of Nephrology

P1476

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

@en

P2093

Alexander Faerman

http://www.w3.org/2001/XMLSchema#string

Anat Brafman

http://www.w3.org/2001/XMLSchema#string

Bruce A Molitoris

http://www.w3.org/2001/XMLSchema#string

Eduard Fridman

http://www.w3.org/2001/XMLSchema#string

Elena Feinstein

http://www.w3.org/2001/XMLSchema#string

Hagar Kalinski

http://www.w3.org/2001/XMLSchema#string

Hagit Ashush

http://www.w3.org/2001/XMLSchema#string

James D Thompson

http://www.w3.org/2001/XMLSchema#string

Pierre C Dagher

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Rami Skaliter

http://www.w3.org/2001/XMLSchema#string

P2860

p53 has a direct apoptogenic role at the mitochondria

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

Death receptors: signaling and modulation

Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury

The biochemistry of apoptosis

The pathophysiology of mitochondrial cell death

A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis.

Two-photon microscopy: visualization of kidney dynamics.

P304

1754-1764

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scholarly article

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10.1681/ASN.2008111204

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8

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20

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2009-05-21T00:00:00Z

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19470675

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2723992

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