Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements.
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Imputation and subset based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33Epigenome-wide Association Studies and the Interpretation of Disease -OmicsEpigenetic Research of Neurodegenerative Disorders Using Patient iPSC-Based ModelsEpigenetics and evolutionGenetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survivalEpigenome data release: a participant-centered approach to privacy protectionWinner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level DataGenome-wide interaction studies reveal sex-specific asthma risk alleles.Associating cellular epigenetic models with human phenotypesEpigenome-wide association of liver methylation patterns and complex metabolic traits in miceMany obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers.Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) dataIntegrative Analysis of Multi-omics Data for Discovery and Functional Studies of Complex Human Diseases.Integrating transcriptome and epigenome: putting together the pieces of the type 2 diabetes pathogenesis puzzle.The background puzzle: how identical mutations in the same gene lead to different disease symptoms.Methylome-wide association study of whole blood DNA in the Norfolk Island isolate identifies robust loci associated with age.The interplay of DNA methylation over time with Th2 pathway genetic variants on asthma risk and temporal asthma transition.Genome-wide DNA methylation analysis reveals loci that distinguish different types of adipose tissue in obese individualsGenetic-epigenetic interactions in cis: a major focus in the post-GWAS eraThe effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes.Epigenetic variation in monozygotic twins: a genome-wide analysis of DNA methylation in buccal cellsRTeQTL: Real-Time Online Engine for Expression Quantitative Trait Loci AnalysesOral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylationGenome-wide investigation of DNA methylation marks associated with FV Leiden mutation.Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarcheGenetic and environmental exposures constrain epigenetic drift over the human life course.Obesity accelerates epigenetic aging of human liver.Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsBiomarkers of coronary artery disease: the promise of the transcriptome.Glutamate receptor gene GRIN2A, coffee, and Parkinson disease.The Influences of Genetic and Environmental Factors on Methylome-wide Association Studies for Human Diseases.An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins.Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors.An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss.Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study.Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent lociQuantitative variability of 342 plasma proteins in a human twin population.Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levelsGenome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat.
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Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Global analysis of DNA methyla ...... in distal regulatory elements.
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Global analysis of DNA methyla ...... in distal regulatory elements.
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type
label
Global analysis of DNA methyla ...... in distal regulatory elements.
@en
Global analysis of DNA methyla ...... in distal regulatory elements.
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prefLabel
Global analysis of DNA methyla ...... in distal regulatory elements.
@en
Global analysis of DNA methyla ...... in distal regulatory elements.
@nl
P2093
P2860
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P1476
Global analysis of DNA methyla ...... in distal regulatory elements.
@en
P2093
Alicja Wilk
Amy Barrett
Elin Grundberg
Emmanouil T Dermitzakis
Eshwar Meduri
James Nisbet
Magdalena Sekowska
Maxime Caron
Multiple Tissue Human Expression Resource Consortium
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P304
P356
10.1016/J.AJHG.2013.10.004
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P577
2013-10-31T00:00:00Z