Piperlongumine induces autophagy by targeting p38 signaling.
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New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of AutophagyLiver kinase B1 regulates the centrosome via PLK1.Anticancer principles from medicinal piper ( hú jiāo) plants.Piperlongumine induces apoptosis and synergizes with cisplatin or paclitaxel in human ovarian cancer cells.Piperlongumine inhibits migration of glioblastoma cells via activation of ROS-dependent p38 and JNK signaling pathways.MAPK14/p38α-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation.Piperlongumine-induced phosphatidylserine translocation in the erythrocyte membranePiperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer.Piperlongumine induces apoptotic and autophagic death of the primary myeloid leukemia cells from patients via activation of ROS-p38/JNK pathways.LKB1 reduces ROS-mediated cell damage via activation of p38.Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP.A Fucus vesiculosus extract inhibits estrogen receptor activation and induces cell death in female cancer cell lines.Discovery of piperlongumine as a potential novel lead for the development of senolytic agents.Piperlongumine and immune cytokine TRAIL synergize to promote tumor deathGlycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells.Piperlongumine Suppresses Proliferation of Human Oral Squamous Cell Carcinoma through Cell Cycle Arrest, Apoptosis and Senescence.Transcriptome Analysis of Piperlongumine-Treated Human Pancreatic Cancer Cells Reveals Involvement of Oxidative Stress and Endoplasmic Reticulum Stress Pathways.Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models.Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells.Redox-directed cancer therapeutics: Taurolidine and Piperlongumine as broadly effective antineoplastic agents (review).A Central Role for Phosphorylated p38α in Linking Proteasome Inhibition-Induced Apoptosis and Autophagy.JNK signaling pathway is involved in piperlongumine-mediated apoptosis in human colorectal cancer HCT116 cells.Piperlongumine induces apoptosis and autophagy in human lung cancer cells through inhibition of PI3K/Akt/mTOR pathway.Natural products as modulator of autophagy with potential clinical prospects.Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine.Elaborating the role of natural products-induced autophagy in cancer treatment: achievements and artifacts in the state of the art.Sinomenine Hydrochloride Inhibits Human Glioblastoma Cell Growth through Reactive Oxygen Species Generation and Autophagy-Lysosome Pathway Activation: An In Vitro and In Vivo Study.Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers.A diphenyldiselenide derivative induces autophagy via JNK in HTB-54 lung cancer cells.Blocking autophagy enhances the apoptotic effect of 18β-glycyrrhetinic acid on human sarcoma cells via endoplasmic reticulum stress and JNK activation.Escin induces caspase-dependent apoptosis and autophagy through the ROS/p38 MAPK signalling pathway in human osteosarcoma cells in vitro and in vivo.Natural agents mediated autophagic signal networks in cancer.Piperlongumine and p53-reactivator APR-246 selectively induce cell death in HNSCC by targeting GSTP1.Piperlongumine induces apoptosis and autophagy in leukemic cells through targeting the PI3K/Akt/mTOR and p38 signaling pathways.Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models.Piperlongumine as a potential activator of AMP-activated protein kinase in HepG2 cells.
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P2860
Piperlongumine induces autophagy by targeting p38 signaling.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Piperlongumine induces autophagy by targeting p38 signaling.
@en
Piperlongumine induces autophagy by targeting p38 signaling.
@nl
type
label
Piperlongumine induces autophagy by targeting p38 signaling.
@en
Piperlongumine induces autophagy by targeting p38 signaling.
@nl
prefLabel
Piperlongumine induces autophagy by targeting p38 signaling.
@en
Piperlongumine induces autophagy by targeting p38 signaling.
@nl
P2093
P2860
P356
P1476
Piperlongumine induces autophagy by targeting p38 signaling.
@en
P2093
P2860
P356
10.1038/CDDIS.2013.358
P577
2013-10-03T00:00:00Z