Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny.
about
Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoireGenetic requirements for the development and differentiation of interleukin-17-producing γδ T cellsTerminal deoxynucleotidyl transferase establishes and broadens antiviral CD8+ T cell immunodominance hierarchiesRegulatory T cells prevent catastrophic autoimmunity throughout the lifespan of miceAnalysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain.Defining critical windows in the development of the human immune system.Ku80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferaseA Highly Focused Antigen Receptor Repertoire Characterizes γδ T Cells That are Poised to Make IL-17 Rapidly in Naive AnimalsAbsence of N addition facilitates B cell development, but impairs immune responses.In Mls-1a mice, fetal-type beta-gene rearrangements are frequent among self-anergic V beta 6 T cells.Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity.Most alpha/beta T cell receptor diversity is due to terminal deoxynucleotidyl transferaseImmune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires.Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells.Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean miceA role for DNA polymerase mu in the emerging DJH rearrangements of the postgastrulation mouse embryo.Heterogeneity in the CD4 T Cell Compartment and the Variability of Neonatal Immune Responsiveness.Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals.Regulatory potential and control of Foxp3 expression in newborn CD4+ T cellsThe two isoforms of mouse terminal deoxynucleotidyl transferase differ in both the ability to add N regions and subcellular localization.Transcription of the lymphocyte-specific terminal deoxynucleotidyltransferase gene requires a specific core promoter structureHuman syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development.Insights into immune system development and function from mouse T-cell repertoires.Transcription of the juvenile hormone esterase gene under the control of both an initiator and AT-rich motif.Dynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians.The immune system as a self-centered network of lymphocytes.Hematopoietic stem cell-independent B-1a lineage.Alterations in the Thymic Selection Threshold Skew the Self-Reactivity of the TCR Repertoire in Neonates.A potential role for Elf-1 in terminal transferase gene regulationThe major histocompatibility complex (MHC) Ea promoter: sequences and factors at the initiation site.Involvement of caspace-3 in the cleavage of terminal transferase.T cell migration during development: homing is not related to TCR V beta 1 repertoire selection.Regulation of the juvenile hormone esterase gene by a composite core promoter.TCR delta gene rearrangements in acute myeloid leukemia with T-lymphoid antigen expression.Repertoires of antigen receptors in Tdt congenitally deficient mice.B cell development in mice.Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor delta transgene.Distribution and development of the postnatal murine Vδ1 T-cell receptor repertoire.Altered immunodominance hierarchies of influenza A virus-specific H-2(b)-restricted CD8+ T cells in the absence of terminal deoxynucleotidyl transferase.
P2860
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P2860
Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Regulation of N-region diversi ...... entiation and thymus ontogeny.
@en
Regulation of N-region diversi ...... entiation and thymus ontogeny.
@nl
type
label
Regulation of N-region diversi ...... entiation and thymus ontogeny.
@en
Regulation of N-region diversi ...... entiation and thymus ontogeny.
@nl
prefLabel
Regulation of N-region diversi ...... entiation and thymus ontogeny.
@en
Regulation of N-region diversi ...... entiation and thymus ontogeny.
@nl
P2093
P2860
P356
P1476
Regulation of N-region diversi ...... entiation and thymus ontogeny.
@en
P2093
P2860
P304
11011-11015
P356
10.1073/PNAS.89.22.11011
P407
P577
1992-11-01T00:00:00Z