Postsynaptic alpha-2 adrenergic receptors are critical for the antidepressant-like effects of desipramine on behavior.
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Changes in postnatal norepinephrine alter alpha-2 adrenergic receptor development.LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy.Lipopolysaccharide-induced depressive-like behavior is associated with α₁-adrenoceptor dependent downregulation of the membrane GluR1 subunit in the mouse medial prefrontal cortex and ventral tegmental areaEffects of psychotropic agents on extinction of lever-press avoidance in a rat model of anxiety vulnerability.α2 adrenergic receptor dysregulation in depressive disorders: implications for the neurobiology of depression and antidepressant therapyParticipation of brainstem monoaminergic nuclei in behavioral depressionAssociation study of three single-nucleotide polymorphisms in the cyclic adenosine monophosphate response element binding 1 gene and major depressive disorder.Noradrenergic antidepressant responses to desipramine in vivo are reciprocally regulated by arrestin3 and spinophilin.RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states.The alpha2 adrenergic receptor antagonist idazoxan, but not the serotonin-2A receptor antagonist M100907, partially attenuated reward deficits associated with nicotine, but not amphetamine, withdrawal in ratsBiphasic Effects of α-Asarone on Immobility in the Tail Suspension Test: Evidence for the Involvement of the Noradrenergic and Serotonergic Systems in Its Antidepressant-Like ActivityMechanisms of antidepressant resistanceTherapeutic Potential of Selectively Targeting the α2C-Adrenoceptor in Cognition, Depression, and Schizophrenia-New Developments and Future Perspective.The Utility of Impulsive Bias and Altered Decision Making as Predictors of Drug Efficacy and Target Selection: Rethinking Behavioral Screening for Antidepressant Drugs.Genetic heterogeneity according to age at onset in bipolar disorder: a combined positional cloning and candidate gene approach.Changes in behavior and ultrasonic vocalizations during antidepressant treatment in the maternally separated Wistar-Kyoto rat model of depression.Role of cortical alpha-2 adrenoceptors in alcohol withdrawal-induced depression and tricyclic antidepressants.The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition.Antidepressant-like effect of extract from Polygala paniculata: involvement of the monoaminergic systems.α₂- and β-adrenoceptors involvement in nortriptyline modulation of auditory sustained attention and impulsivity.
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P2860
Postsynaptic alpha-2 adrenergic receptors are critical for the antidepressant-like effects of desipramine on behavior.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Postsynaptic alpha-2 adrenergi ...... ts of desipramine on behavior.
@en
Postsynaptic alpha-2 adrenergi ...... ts of desipramine on behavior.
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type
label
Postsynaptic alpha-2 adrenergi ...... ts of desipramine on behavior.
@en
Postsynaptic alpha-2 adrenergi ...... ts of desipramine on behavior.
@nl
prefLabel
Postsynaptic alpha-2 adrenergi ...... ts of desipramine on behavior.
@en
Postsynaptic alpha-2 adrenergi ...... ts of desipramine on behavior.
@nl
P2093
P2860
P356
P1476
Postsynaptic alpha-2 adrenergi ...... ts of desipramine on behavior.
@en
P2093
Han-Ting Zhang
James M O'Donnell
Lisa R Whisler
Yang Xiang
Ying Huang
P2860
P2888
P304
P356
10.1038/NPP.2008.184
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P577
2008-10-15T00:00:00Z
P5875
P6179
1006617966