Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats.
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Cumulative effects of in utero administration of mixtures of reproductive toxicants that disrupt common target tissues via diverse mechanisms of toxicityGene expression in the fetal mouse ovary is altered by exposure to low doses of bisphenol AEnvironmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humansLow-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research RecommendationsPhthalates and diet: a review of the food monitoring and epidemiology dataUrinary phthalate metabolites and ovarian reserve among women seeking infertility careIdentification of phthalates in medications and dietary supplement formulations in the United States and CanadaRodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dustThe intersection of neurotoxicology and endocrine disruption.Targeting testis-specific proteins to inhibit spermatogenesis: lesson from endocrine disrupting chemicals.Dietary phthalate exposure in pregnant women and the impact of consumer practices.Interpretation of studies on the developmental reproductive toxicology of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspringLong-term effects of maternal exposure to Di (2-ethylhexyl) Phthalate on sperm and testicular parameters in Wistar rats offspring.In utero exposure to an AR antagonist plus an inhibitor of fetal testosterone synthesis induces cumulative effects on F1 male rats.Association between maternal exposure to di(2-ethylhexyl) phthalate and reproductive hormone levels in fetal blood: the Hokkaido study on environment and children's health.Simvastatin and dipentyl phthalate lower ex vivo testicular testosterone production and exhibit additive effects on testicular testosterone and gene expression via distinct mechanistic pathways in the fetal rat.A critical assessment of the endocrine susceptibility of the human testis to phthalates from fetal life to adulthood.Children's phthalate intakes and resultant cumulative exposures estimated from urine compared with estimates from dust ingestion, inhalation and dermal absorption in their homes and daycare centers.Man is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetusEffects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability.Daily exposure to Di(2-ethylhexyl) phthalate alters estrous cyclicity and accelerates primordial follicle recruitment potentially via dysregulation of the phosphatidylinositol 3-kinase signaling pathway in adult mice.Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency.A short-term in vivo screen using fetal testosterone production, a key event in the phthalate adverse outcome pathway, to predict disruption of sexual differentiationExposure to Endocrine Disruptors and Nuclear Receptors Gene Expression in Infertile and Fertile Men from Italian Areas with Different Environmental Features.Phthalate release in leachate from municipal landfills of central Poland.Dose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in RatsOf mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent.Non-monotonic dose effects of in utero exposure to di(2-ethylhexyl) phthalate (DEHP) on testicular and serum testosterone and anogenital distance in male mouse fetuses.Exposures to endocrine-disrupting chemicals and age of menarche in adolescent girls in NHANES (2003-2008).Neonatal phthalate ester exposure induced placental MTs, FATP1 and HFABP mRNA expression in two districts of southeast China.Epigenetic transgenerational effects of endocrine disruptors on male reproduction.Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity: Lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates.Integrative rodent models for assessing male reproductive toxicity of environmental endocrine active substancesChallenges in the application of quantitative approaches in risk assessment: a case study with di-(2-ethylhexyl)phthalate.Exposure to modern, widespread environmental endocrine disrupting chemicals and their effect on the reproductive potential of women: an overview of current epidemiological evidence.Occurrence of phthalates in aquatic environment and their removal during wastewater treatment processes: a review.Prenatal phthalate exposure: epigenetic changes leading to lifelong impact on steroid formation.A Novel Method for Calculating Potency-Weighted Cumulative Phthalates Exposure with Implications for Identifying Racial/Ethnic Disparities among U.S. Reproductive-Aged Women in NHANES 2001-2012.Cumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment.Investigations of putative reproductive toxicity of low-dose exposures to flutamide in Wistar rats.
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P2860
Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mechanisms of action of phthal ...... pment in male laboratory rats.
@en
Mechanisms of action of phthal ...... pment in male laboratory rats.
@nl
type
label
Mechanisms of action of phthal ...... pment in male laboratory rats.
@en
Mechanisms of action of phthal ...... pment in male laboratory rats.
@nl
prefLabel
Mechanisms of action of phthal ...... pment in male laboratory rats.
@en
Mechanisms of action of phthal ...... pment in male laboratory rats.
@nl
P2093
P1476
Mechanisms of action of phthal ...... pment in male laboratory rats.
@en
P2093
Cynthia V Rider
Kembra L Howdeshell
L Earl Gray
P304
P356
10.1016/J.ENVRES.2008.08.009
P577
2008-10-01T00:00:00Z