Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 04 October 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients

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Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients.

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type

Item

label

Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients

@en

Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients.

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prefLabel

Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients

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Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients.

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P1476

Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients

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P2093

Dave Singh

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Isabel Ramis

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James Pearson

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Jonathan Plumb

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Martin D Lehner

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Montserrat Miralpeix

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Thomas Southworth

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Vandana Gupta

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P2860

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage

TH2 cytokine-associated transcription factors in atopic and nonatopic asthma: evidence for differential signal transducer and activator of transcription 6 expression

Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model

Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma

Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis.

TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein.

Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma.

Type 2 inflammation in asthma--present in most, absent in many

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s12931-016-0436-2

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scholarly article

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10.1186/S12931-016-0436-2

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P478

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2016-10-04T00:00:00Z

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1044926127

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27716212

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asthma

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5051065

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