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Biosynthesis of phosphonic and phosphinic acid natural products.

Biosynthesis of phosphonic and phosphinic acid natural products.

http://www.wikidata.org/entity/Q37311884

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On the stereochemistry of 2-hydroxyethylphosphonate dioxygenase Mechanism and substrate recognition of 2-hydroxyethylphosphonate dioxygenase Synthesis of methylphosphonic acid by marine microbes: a source for methane in the aerobic ocean Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways Prodrugs of phosphonates and phosphates: crossing the membrane barrier Radical-mediated enzymatic methylation: a tale of two SAMS Characterization and structure of DhpI, a phosphonateO-methyltransferase involved in dehydrophos biosynthesis Structure of the Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors Structural and Mechanistic Insights into C-P Bond Hydrolysis by Phosphonoacetate Hydrolase Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases Structure and Function of Phosphonoacetaldehyde Dehydrogenase: The Missing Link in Phosphonoacetate Formation Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates Phylogenomic Analysis of Natural Products Biosynthetic Gene Clusters Allows Discovery of Arseno-Organic Metabolites in Model Streptomycetes Molecular cloning and heterologous expression of the dehydrophos biosynthetic gene cluster Biosynthesis of rhizocticins, antifungal phosphonate oligopeptides produced by Bacillus subtilis ATCC6633 The genes and enzymes of phosphonate metabolism by bacteria, and their distribution in the marine environment Cyanohydrin phosphonate natural product from Streptomyces regensis.Utilization of glyphosate as phosphate source: biochemistry and genetics of bacterial carbon-phosphorus lyase.Stereochemistry of Hydride Transfer by Group III Alcohol Dehydrogenases Involved in Phosphonate Biosynthesis Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin.Phosphatase-inert glucosamine 6-phosphate mimics serve as actuators of the glmS riboswitch.Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes Biosynthesis of fosfazinomycin is a convergent process.Alternative pathways for phosphonate metabolism in thermophilic cyanobacteria from microbial mats.Structure-activity relationships of the phosphonate antibiotic dehydrophos.In vitro phosphinate methylation by PhpK from Kitasatospora phosalacinea Combinatorial pathway engineering for optimized production of the anti-malarial FR900098.Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Heterotrophic bacteria from an extremely phosphate-poor lake have conditionally reduced phosphorus demand and utilize diverse sources of phosphorus.A common late-stage intermediate in catalysis by 2-hydroxyethyl-phosphonate dioxygenase and methylphosphonate synthase.Modular Synthesis of Novel Macrocycles Bearing α,β-Unsaturated Chemotypes through a Series of One-Pot, Sequential Protocols.Different biosynthetic pathways to fosfomycin in Pseudomonas syringae and Streptomyces species.Mechanistic investigation of methylphosphonate synthase, a non-heme iron-dependent oxygenase.Investigation of enzymatic C-P bond formation using multiple quantum HCP nuclear magnetic resonance spectroscopy Nonribosomal Peptide Synthesis-Principles and Prospects.Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases.Conserved biosynthetic pathways for phosalacine, bialaphos and newly discovered phosphonic acid natural products.Answers to the carbon-phosphorus lyase conundrum.Probing a coral genome for components of the photoprotective scytonemin biosynthetic pathway and the 2-aminoethylphosphonate pathway

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P2860

Biosynthesis of phosphonic and phosphinic acid natural products.

http://www.wikidata.org/entity/Q37311884

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on January 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Biosynthesis of phosphonic and phosphinic acid natural products.

@en

Biosynthesis of phosphonic and phosphinic acid natural products.

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type

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Biosynthesis of phosphonic and phosphinic acid natural products.

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Biosynthesis of phosphonic and phosphinic acid natural products.

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prefLabel

Biosynthesis of phosphonic and phosphinic acid natural products.

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Biosynthesis of phosphonic and phosphinic acid natural products.

@nl

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ANNUREV.BIOCHEM.78.091707.100215

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Annual Review of Biochemistry

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Biosynthesis of phosphonic and phosphinic acid natural products

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William W Metcalf

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P2860

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

Determination of the substrate binding mode to the active site iron of (S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analogues

Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation

Helix swapping between two alpha/beta barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg(2+)-oxalate

The reaction cycle of isopenicillin N synthase observed by X-ray diffraction

Dissociative phosphoryl transfer in PEP mutase catalysis: structure of the enzyme/sulfopyruvate complex and kinetic properties of mutants

Degradation pathway of the phosphonate ciliatine: crystal structure of 2-aminoethylphosphonate transaminase

Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin

Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

Radical mechanisms of enzymatic catalysis

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65-94

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scholarly article

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10.1146/ANNUREV.BIOCHEM.78.091707.100215

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78

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Wilfred A van der Donk

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2009-01-01T00:00:00Z

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