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Bigger, better, faster: principles and models of AKAP anchoring protein signaling.Influence of parameter values on the oscillation sensitivities of two p53-Mdm2 modelsMolecular signaling network motifs provide a mechanistic basis for cellular threshold responsesClassifying the topology of AHL-driven quorum sensing circuits in proteobacterial genomesReverse engineering and identification in systems biology: strategies, perspectives and challengesFeedback loops and reciprocal regulation: recurring motifs in the systems biology of the cell cycleBeyond symmetry-breaking: competition and negative feedback in GTPase regulationA network-oriented perspective on cardiac calcium signalingQuantifying the dynamics of coupled networks of switches and oscillatorsChanges in oscillatory dynamics in the cell cycle of early Xenopus laevis embryosMouse hair cycle expression dynamics modeled as coupled mesenchymal and epithelial oscillatorsA Systemized Approach to Investigate Ca(2+) Synchronization in Clusters of Human Induced Pluripotent Stem-Cell Derived CardiomyocytesA perspective on bridging scales and design of models using low-dimensional manifolds and data-driven model inferenceQuantitative and logic modelling of molecular and gene networksAdaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety AssessmentA simple negative interaction in the positive transcriptional feedback of a single gene is sufficient to produce reliable oscillationsTopology and dynamics of the zebrafish segmentation clock core circuitPhase resetting reveals network dynamics underlying a bacterial cell cycleThe Goodwin model: behind the Hill functionSystems modeling of anti-apoptotic pathways in prostate cancer: psychological stress triggers a synergism pattern switch in drug combination therapyPositive feedback promotes oscillations in negative feedback loopsRobust concentration and frequency control in oscillatory homeostatsFrom Physics to Pharmacology?A comprehensive molecular interaction map of the budding yeast cell cycle.Systematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network.Modelling emergence of oscillations in communicating bacteria: a structured approach from one to many cellsNegative feedback enhances robustness in the yeast polarity establishment circuit.Oscillatory dynamics of Cdc42 GTPase in the control of polarized growth.Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.The bacterial cell division proteins FtsA and FtsZ self-organize into dynamic cytoskeletal patternsUNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity.Computer simulations of the mouse spermatogenic cycle.Oscillatory serotonin function in depression.Noise Reduction in Complex Biological Switches.How to turn a genetic circuit into a synthetic tunable oscillator, or a bistable switchTuning genetic clocks employing DNA binding sites.Avoiding transcription factor competition at promoter level increases the chances of obtaining oscillation.Molecular mechanisms that regulate the coupled period of the mammalian circadian clockThe molecular clockwork of a protein-based circadian oscillator.Reliability of transcriptional cycles and the yeast cell-cycle oscillator.
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
gotara zanistî
@ku-latn
scientific article published on 30 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
name
Design principles of biochemical oscillators.
@en
Design principles of biochemical oscillators.
@nl
type
label
Design principles of biochemical oscillators.
@en
Design principles of biochemical oscillators.
@nl
prefLabel
Design principles of biochemical oscillators.
@en
Design principles of biochemical oscillators.
@nl
P2860
P356
P1476
Design principles of biochemical oscillators.
@en
P2093
Béla Novák
P2860
P2888
P304
P356
10.1038/NRM2530
P50
P577
2008-10-30T00:00:00Z