UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.
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LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retinaNuclear migration events throughout developmentThe molecular basis of emerin-emerin and emerin-BAF interactionsThe nuclear envelope at a glanceKDP-1 is a nuclear envelope KASH protein required for cell-cycle progressionMAP and kinesin-dependent nuclear positioning is required for skeletal muscle functionThe auto-inhibitory domain and ATP-independent microtubule-binding region of Kinesin heavy chain are major functional domains for transport in the Drosophila germline.Translocating myonuclei have distinct leading and lagging edges that require kinesin and dyneinThe SUN protein UNC-84 is required only in force-bearing cells to maintain nuclear envelope architecture.Kinesin-dependent transport results in polarized migration of the nucleus in oocytes and inward movement of yolk granules in meiotic embryosInteractions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus.The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration.Kinesin-1 and dynein at the nuclear envelope mediate the bidirectional migrations of nucleiLINC complexes in health and disease.Novel isoforms of the transport regulator klar.Bi-directional transport of the nucleus by dynein and kinesin-1.Accessorizing and anchoring the LINC complex for multifunctionality.Multiple mechanisms actively target the SUN protein UNC-84 to the inner nuclear membrane.Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.Nuclear envelope in nuclear positioning and cell migrationVAB-10 spectraplakin acts in cell and nuclear migration in Caenorhabditis elegansMaking the LINC: SUN and KASH protein interactions.The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts.The branched actin nucleator Arp2/3 promotes nuclear migrations and cell polarity in the C. elegans zygote.Validation of a Mouse Model to Disrupt LINC Complexes in a Cell-specific Mannertoca-1 is in a novel pathway that functions in parallel with a SUN-KASH nuclear envelope bridge to move nuclei in Caenorhabditis elegans.Connecting the nucleus to the cytoskeleton by SUN-KASH bridges across the nuclear envelope.Kinesin-1 acts with netrin and DCC to maintain sensory neuron position in Caenorhabditis elegans.The diverse functional LINCs of the nuclear envelope to the cytoskeleton and chromatinControl of oocyte growth and meiotic maturation in Caenorhabditis elegans.Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections.Nuclear positioning in muscle development and disease.Developmental regulation of linkers of the nucleoskeleton to the cytoskeleton during mouse postnatal retinogenesis.LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining.Temporal and tissue-specific disruption of LINC complexes in vivo.How plants LINC the SUN to KASH.Gathering up meiotic telomeres: a novel function of the microtubule-organizing center.Microtubules as key coordinators of nuclear envelope and endoplasmic reticulum dynamics during mitosis.Cell Biology of the Caenorhabditis elegans Nucleus.
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UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.
@en
UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.
@nl
type
label
UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.
@en
UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.
@nl
prefLabel
UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.
@en
UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.
@nl
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UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration
@en
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Francis J McNally
Heidi N Fridolfsson
Marina Meyerzon
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P304
P356
10.1242/DEV.038596
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2009-07-15T00:00:00Z